Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 14/20 | 0.55 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL90991 | 1.00 | ADK (0.55) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL91053 | 0.90 | ADK (0.59) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL10069367 | 0.84 | ADK (0.49) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL25027456 | 0.77 | ADK (0.69) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL6685798 | 0.76 | ADK (0.71) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL59610 | 0.75 | DPP4 (0.74) | DOT1LPRMT5WDR77 | |
| SCHEMBL173151 | 0.75 | DPP4 (0.74) | DOT1LPRMT5WDR77 | |
| SCHEMBL13986299 | 0.75 | DPP4 (0.74) | DOT1LPRMT5WDR77 | |
| SCHEMBL20419130 | 0.71 | ADK (0.71) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL22399485 | 0.71 | ADK (0.71) | ADKDOT1LNPC1GALR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129106-B2 | Sequence-specific detection of methylation in biomolecules | Max-Planck-Geselischaft zur Forderung der Wissenschaften E.V. (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20110165564-A1 | SEQUENCE-SPECIFIC DETECTION OF METHYLATION IN BIOMOLECULES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165564-A1 | SEQUENCE-SPECIFIC DETECTION OF METHYLATION IN BIOMOLECULES | DNMT1, MAT2B, AHCY | ADK 291/4885DOT1L 132/4885NPC1 4773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.