Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069632 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM5BMAPK14POLBRECQL | |
| SCHEMBL10069623 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MAPK14POLBRECQLSMN1; SMN2 | |
| SCHEMBL10069613 | 0.85 | ALDH1A1 (0.40) | ALDH1A1POLBRECQLSMN1; SMN2NPC1 | |
| SCHEMBL10069591 | 0.85 | ESR1 (0.35) | ALDH1A1KDM5BALOX5ERCC5FEN1 | |
| SCHEMBL10069625 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KDM5BMAPK14POLBRECQL | |
| SCHEMBL10069621 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPK14SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1287915 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPK14POLBRECQLSMN1; SMN2 | |
| SCHEMBL10069600 | 0.82 | AR (0.42) | ALDH1A1POLBNPC1RAB9AKDM4E | |
| SCHEMBL10069617 | 0.81 | ALDH1A1 (0.35) | ALDH1A1MAPK14POLBCNOT7ERCC5 | |
| SCHEMBL1687638 | 0.79 | ADORA2A (0.36) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |