Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069597 | 0.92 | ANO1 (0.36) | ESR1LMNAKDM5BPDE10A | |
| SCHEMBL10069590 | 0.89 | ALDH1A1 (0.39) | ALDH1A1LMNAIDH1KDM5BMAPK1 | |
| SCHEMBL10069606 | 0.87 | ALDH1A1 (0.37) | ALDH1A1CASRLMNAKMT2AIDH1 | |
| SCHEMBL10069595 | 0.86 | ALDH1A1 (0.38) | ALDH1A1LMNAIDH1MAPK1ERCC5 | |
| SCHEMBL10069601 | 0.86 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AMAPK1ERCC5 | |
| SCHEMBL10069594 | 0.86 | MAPT (0.38) | ALDH1A1LMNAERCC5FEN1USP2 | |
| SCHEMBL10069630 | 0.85 | ALDH1A1 (0.38) | ESR1ALDH1A1ALOX5KDM5BMAPK1 | |
| SCHEMBL10069592 | 0.84 | MEN1 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL10069620 | 0.82 | MAPK1 (0.36) | ALDH1A1CASRMAPK1ERCC5FEN1 | |
| SCHEMBL10069611 | 0.82 | L3MBTL1 (0.36) | ALDH1A1USP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |