Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1687638 | 0.94 | ADORA2A (0.36) | ALDH1A1SLC34A1HSD17B10L3MBTL1AR | |
| SCHEMBL10069632 | 0.92 | ALDH1A1 (0.43) | ALDH1A1MAPK14POLBRECQLSMN1; SMN2 | |
| SCHEMBL10069623 | 0.90 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPK14AR | |
| SCHEMBL10069621 | 0.89 | ALDH1A1 (0.39) | ALDH1A1GRM5CYP1A2KMT2AHSD17B10 | |
| SCHEMBL10069600 | 0.85 | AR (0.42) | ALDH1A1MEN1KMT2AARPOLB | |
| SCHEMBL10069630 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MAPK14POLBRECQLSMN1; SMN2 | |
| SCHEMBL10069625 | 0.85 | ALDH1A1 (0.41) | ALDH1A1GRM5MAPK14POLBRECQL | |
| SCHEMBL10069601 | 0.84 | ALDH1A1 (0.36) | ALDH1A1CYP2C9CYP2C19GRM5MEN1 | |
| SCHEMBL10069613 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AL3MBTL1AR | |
| SCHEMBL1287928 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SLC34A1CYP2C9CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |