Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | APEX1 | P27695 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070195 | 1.00 | ALDH1A1 (0.72) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL22241270 | 0.91 | ALDH1A1 (0.81) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL10070187 | 0.91 | NR1H4 (0.59) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL26544652 | 0.90 | ALDH1A1 (0.72) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL7868896 | 0.89 | NPC1 (0.83) | ALDH1A1LMNANPC1RAB9AL3MBTL1 | |
| SCHEMBL28658865 | 0.87 | NPC1 (0.66) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL3093928 | 0.86 | LMNA (0.74) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| Avobenzone SCHEMBL1768910 | 0.84 | ALDH1A1 (1.00) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| Avobenzone SCHEMBL15650 | 0.84 | ALDH1A1 (1.00) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL5608126 | 0.83 | ESRRG (0.63) | ALDH1A1LMNAALOX15APEX1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116623198-A | Method for preparing aromatic carbonyl compound by electrochemical oxidation reaction and aromatic carbonyl compound | 南开大学 | 2023-08-22 | — | — | CN | disclosed |
| US-20230210755-A1 | FUNCTIONAL SKIN COATING POLYMER | THE JOHNS HOPKINS UNIVERSITY | 2023-07-06 | — | — | US | disclosed |
| US-20230210755-A1 | FUNCTIONAL SKIN COATING POLYMER | THE JOHNS HOPKINS UNIVERSITY | 2023-07-06 | — | — | US | disclosed |
| EP-2600854-B1 | PHENETHYL, PHENETHYLENE, PHENETHYNE AND INDANONE DERIVATES IN COSMETIC FORMULATIONS, ESPECIALLY FOR USE IN SKIN AGEING PROCESSES | MERCK PATENT GMBH (DE) | 2016-01-27 | — | — | EP | disclosed |
| WO-2012016619-A1 | PHENETHYL, PHENETHYLENE, PHENETHYNE AND INDANONE DERIVATES IN COSMETIC FORMULATIONS, ESPECIALLY FOR USE IN SKIN AGEING PROCESSES | MERCK PATENT GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210755-A1 | FUNCTIONAL SKIN COATING POLYMER | CUTA, PUF60, SUN2 | ALDH1A1 1197/4885LMNA 2192/4885ALOX15 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.