SCHEMBL10070482

SCHEMBL10070482

Bc1ccccc1C(=O)Nc1ccccc1Nc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.56
MEN1 O00255 6/20 0.54
KMT2A Q03164 6/20 0.54
MAPT P10636 3/20 0.49
ALOX15 P16050 1/20 0.49
RXFP1 Q9HBX9 2/20 0.48
SIRT2 Q8IXJ6 2/20 0.48
KDM4E B2RXH2 2/20 0.48
TDP1 Q9NUW8 1/20 0.47
NPC1 O15118 2/20 0.46
RAB9A P51151 1/20 0.46
ALDH1A1 P00352 2/20 0.46
HTT P42858 3/20 0.45
HPGD P15428 3/20 0.45
LMNA P02545 2/20 0.45
TP53 P04637 2/20 0.45
GAA P10253 2/20 0.45
HSD17B10 Q99714 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14388924 0.83 ALDH1A1 (0.66) MEN1KMT2AMAPTKDM4ETDP1
SCHEMBL358066 0.81 KMT2A (0.72) FABP4MEN1KMT2AMAPTRXFP1
SCHEMBL6140750 0.78 SIRT2 (0.59) FABP4MEN1KMT2AMAPTSIRT2
SCHEMBL12076664 0.77 MEN1 (0.58) FABP4MEN1KMT2AMAPTALOX15
SCHEMBL14281039 0.76 TOP1 (0.58) FABP4MEN1KMT2AMAPTSIRT2
SCHEMBL14034306 0.76 MAPT (0.43) MEN1KMT2AMAPTKDM4ENPC1
SCHEMBL6824227 0.75 MAPT (0.70) FABP4MEN1KMT2AMAPTALOX15
SCHEMBL28511621 0.75 MEN1 (0.51) FABP4MEN1KMT2AMAPTALOX15
SCHEMBL28511622 0.74 ALDH1A1 (0.49) FABP4MEN1KMT2AMAPTALOX15
SCHEMBL338745 0.72 SIRT2 (0.56) FABP4MEN1KMT2ASIRT2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120016449-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120016449-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS TYR, PPOX, CRY1 FABP4 4441/4885MEN1 2684/4885KMT2A 710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.