Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070604 | 0.86 | KMT2A (0.42) | KMT2AALDH1A1LMNACACNA1HCYP2D6 | |
| SCHEMBL10070588 | 0.76 | ALDH1A1 (0.59) | KMT2AALDH1A1LMNAMAPTPKM | |
| SCHEMBL27905216 | 0.65 | CYP3A4 (0.46) | KMT2AALDH1A1CYP2D6MAPT | |
| SCHEMBL34469442 | 0.62 | TP53 (0.43) | ALDH1A1KCNH2MAPT | |
| SCHEMBL34470033 | 0.62 | TP53 (0.43) | ALDH1A1 | |
| SCHEMBL18570582 | 0.62 | APP (0.43) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL2010540 | 0.62 | HRH3 (0.40) | KMT2AALDH1A1CACNA1HMAPTNPSR1 | |
| SCHEMBL25243115 | 0.61 | SMN1; SMN2 (0.37) | KMT2AALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL626776 | 0.61 | MAPT (0.44) | KMT2ACACNA1HCYP2D6KCNH2MAPT | |
| SCHEMBL4300945 | 0.61 | NPSR1 (0.65) | KMT2AALDH1A1LMNAMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020221-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |