Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070586 | 0.86 | KMT2A (0.41) | KMT2AALDH1A1LMNAMAPTCACNA1H | |
| SCHEMBL10070588 | 0.69 | ALDH1A1 (0.59) | KMT2AALDH1A1LMNAMAPTPKM | |
| SCHEMBL626776 | 0.64 | MAPT (0.44) | KMT2AMAPTCACNA1HCYP2D6KCNH2 | |
| SCHEMBL15795578 | 0.62 | ENPP2 (0.56) | KMT2AALDH1A1LMNAMAPTKCNH2 | |
| SCHEMBL15795552 | 0.60 | ENPP2 (0.58) | KCNH2ENPP2SIGMAR1 | |
| SCHEMBL10070602 | 0.60 | PDK1 (0.40) | KMT2AALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10071127 | 0.60 | TACR1 (0.39) | KMT2AMAPTCYP2D6TSHRMEN1 | |
| SCHEMBL4300945 | 0.59 | NPSR1 (0.65) | KMT2AALDH1A1LMNAMAPTPKM | |
| SCHEMBL15795739 | 0.59 | ENPP2 (0.60) | CACNA1HCYP2D6KCNH2ENPP2SIGMAR1 | |
| SCHEMBL4302256 | 0.59 | MAPT (0.63) | KMT2AALDH1A1MAPTCACNA1HCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020221-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |