SCHEMBL25243115

SCHEMBL25243115

Nc1cc(Cl)cc(NCCOCCOCCOCCOCCOCCNC(=O)O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.37
PYGL P06737 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 3/20 0.33
FBP1 P09467 2/20 0.33
MAPT P10636 2/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 2/20 0.33
ALDH1A1 P00352 2/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA4 P22748 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 2/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30547938 0.83 IDO1 (0.44) CA12CA1CA2CA9
SCHEMBL25246656 0.80 MEN1 (0.39) SMN1; SMN2MEN1KMT2AMAPTTDP1
SCHEMBL25189522 0.73 SMN1; SMN2 (0.57) SMN1; SMN2MAPTLMNAALDH1A1RAB9A
SCHEMBL23884332 0.73 SMN1; SMN2 (0.57) SMN1; SMN2MAPTLMNAALDH1A1RAB9A
SCHEMBL16444001 0.71 ALDH1A1 (0.54) SMN1; SMN2MEN1KMT2AMAPTTDP1
SCHEMBL8958557 0.70 MEN1 (0.52) SMN1; SMN2PYGLMEN1KMT2AKDM4E
SCHEMBL9447837 0.70 MEN1 (0.52) SMN1; SMN2PYGLMEN1KMT2AKDM4E
SCHEMBL8958237 0.70 MEN1 (0.52) SMN1; SMN2PYGLMEN1KMT2AKDM4E
SCHEMBL8958401 0.70 MEN1 (0.52) SMN1; SMN2PYGLMEN1KMT2AKDM4E
SCHEMBL18173574 0.70 MEN1 (0.52) SMN1; SMN2PYGLMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190938-A1 NOVEL CARGO DELIVERY SYSTEM AND COMPOSITION COMPRISING THE SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190938-A1 NOVEL CARGO DELIVERY SYSTEM AND COMPOSITION COMPRISING THE SAME ATG7, SQSTM1, BECN1 SMN1; SMN2 1473/4885PYGL 1104/4885MEN1 4549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.