Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070586 | 0.76 | KMT2A (0.41) | ALDH1A1LMNAKMT2ASMN1; SMN2PKM | |
| SCHEMBL626318 | 0.75 | L3MBTL1 (0.53) | LMNAKMT2AL3MBTL1ATMFAAH | |
| SCHEMBL30380956 | 0.75 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1SMN1; SMN2POLBHRH3 | |
| SCHEMBL17152798 | 0.74 | DRD4 (0.43) | ALDH1A1LMNAKMT2AL3MBTL1ATM | |
| SCHEMBL2932454 | 0.73 | L3MBTL1 (0.54) | ALDH1A1LMNAKMT2AL3MBTL1ATM | |
| SCHEMBL23213253 | 0.72 | HRH3 (0.51) | ALDH1A1LMNAL3MBTL1AKR1C3SMN1; SMN2 | |
| SCHEMBL29796217 | 0.72 | HRH3 (0.51) | ALDH1A1LMNAL3MBTL1AKR1C3SMN1; SMN2 | |
| SCHEMBL10070604 | 0.69 | KMT2A (0.42) | ALDH1A1LMNAKMT2AFAAHSMN1; SMN2 | |
| SCHEMBL20570029 | 0.69 | ATM (0.47) | ALDH1A1LMNAKMT2AL3MBTL1ATM | |
| SCHEMBL8514033 | 0.69 | LMNA (0.57) | ALDH1A1LMNAKMT2AATMFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020221-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |