Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156590 | 0.80 | KDM4E (0.51) | CNR1ALDH1A1KDM4EBLMGLA | |
| SCHEMBL27353884 | 0.76 | ESRRG (0.54) | TAAR1CNR1KDM4ECYP2C19L3MBTL1 | |
| SCHEMBL22645024 | 0.76 | NAMPT (0.49) | TDP1CA1CA2MAPT | |
| SCHEMBL17131842 | 0.73 | HPGD (0.55) | CNR1ALDH1A1KMT2ATDP1HPGD | |
| SCHEMBL2729666 | 0.72 | TAAR1 (0.48) | TAAR1ALDH1A1KDM4EHTR1AADRA2A | |
| SCHEMBL9771418 | 0.72 | TAAR1 (0.48) | TAAR1ALDH1A1KDM4EHTR1AADRA2A | |
| SCHEMBL15599543 | 0.71 | TAAR1 (0.52) | TAAR1ALDH1A1KDM4EHTR1AADRA2A | |
| SCHEMBL14640609 | 0.71 | CNR1 (0.58) | TAAR1CNR1CYP2C19L3MBTL1CYP1A2 | |
| SCHEMBL5408045 | 0.70 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2ATDP1GLA | |
| SCHEMBL23963160 | 0.69 | TAAR1 (0.45) | TAAR1ALDH1A1KDM4EHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020221-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |