Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | F13A1 | P00488 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10826205 | 0.83 | MTNR1A (0.50) | KDM4EF13A1SMN1; SMN2ALDH1A1MTNR1A | |
| SCHEMBL10070605 | 0.80 | TAAR1 (0.38) | KDM4ESMN1; SMN2ALDH1A1GLAMAPT | |
| SCHEMBL22645024 | 0.80 | NAMPT (0.49) | MAPT | |
| SCHEMBL171693 | 0.78 | MAPT (0.65) | KDM4EF13A1SMN1; SMN2ALDH1A1MTNR1A | |
| SCHEMBL8535693 | 0.78 | KDM4E (0.59) | KDM4EF13A1SMN1; SMN2ALDH1A1MTNR1A | |
| SCHEMBL24541407 | 0.78 | KMT2A (0.59) | KDM4EF13A1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1469234 | 0.78 | AOC3 (0.59) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| Sulfuric Acid SCHEMBL11083725 | 0.77 | PKM (0.47) | KDM4ESMN1; SMN2ALDH1A1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL20771919 | 0.76 | AOC3 (0.62) | KDM4ESMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL18673198 | 0.76 | MTNR1A (0.42) | KDM4EF13A1SMN1; SMN2ALDH1A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11845751-B2 | Triazolotriazine derivatives as A2A receptor antagonists | ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD. (CN) | 2023-12-19 | — | — | US | disclosed |
| US-20210332055-A1 | TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS | ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD. (CN) | 2021-10-28 | — | — | US | disclosed |
| US-7972388-B2 | Methods and kits for maintaining the condition of colored hair | L'OREAL S.A. (FR) | 2011-07-05 | — | — | US | disclosed |
| US-20100254924-A1 | METHODS AND KITS FOR MAINTAINING THE CONDITION OF COLORED HAIR | LORÉAL (FR) | 2010-10-07 | — | — | US | disclosed |
| US-20100233114-A1 | METHODS OF STYLING HAIR | L'ORéAL S.A. (FR) | 2010-09-16 | — | — | US | disclosed |
| US-7696140-B2 | Composition containing a phospholipid and quaternary ammonium polymer | L'OREAL S.A. (FR) | 2010-04-13 | — | — | US | disclosed |
| US-7611544-B2 | Methods of artificially coloring hair | L'OREAL S.A. (FR) | 2009-11-03 | — | — | US | disclosed |
| US-7601179-B2 | Methods of preserving artificial coloring on keratin materials | L'OREAL S.A. (FR) | 2009-10-13 | — | — | US | disclosed |
| US-20090074701-A1 | METHODS OF ARTIFICIALLY COLORING HAIR | L'OREAL S.A. (FR) | 2009-03-19 | — | — | US | disclosed |
| US-20090074702-A1 | applying to an artificially-colored haira formulation comprising siloxysilicate resin and hexamethylene undecanamide (nylon 6,11/dimethicone copolymer, forms a film on the hair which fixes the artificial colorant to the hair | L'OREAL S.A. (FR) | 2009-03-19 | — | — | US | disclosed |
| US-20080124296-A1 | COMPOSITIONS CONTAINING MICROSPHERES | L'OREAL S.A. (FR) | 2008-05-29 | — | — | US | disclosed |
| WO-2008042606-A2 | COMPOSITIONS CONTAINING QUATERNARY AMMONIUM POLYMERS | L'OREAL S.A. (FR) | 2008-04-10 | — | — | WO | disclosed |
| US-20080085849-A1 | Compositions containing quaternary ammonium polymers | L'OREAL (FR) | 2008-04-10 | — | — | US | disclosed |
| US-20070256254-A1 | Conditioning cream color base having improved color deposition properties | L'OREAL (FR) | 2007-11-08 | — | — | US | disclosed |
| EP-1852103-A2 | Conditioning cream color base having good color deposition properties. | L'Oréal (FR) | 2007-11-07 | — | — | EP | disclosed |
| US-5900028-A | Oxidation dye composition for keratin fibres comprising 2-amino-3-hydroxypyridine and a P-phenylenediamine or P-aminophenol oxidation base, and dyeing process | L 'OREAL (FR) | 1999-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090074701-A1 | METHODS OF ARTIFICIALLY COLORING HAIR | HDAC10, RARA, PRDM7 | KDM4E 936/4885F13A1 2625/4885SMN1; SMN2 3944/4885 |
| US-11845751-B2 | Triazolotriazine derivatives as A2A receptor antagonists | ADORA2A, ADORA1, ADORA3 | KDM4E 3952/4885F13A1 2447/4885SMN1; SMN2 4178/4885 |
| US-20090074702-A1 | applying to an artificially-colored haira formulation comprising siloxysilicate resin and hexamethylene undecanamide (nylon 6,11/dimethicone copolymer, forms a film on the hair which fixes the artificial colorant to the hair | KRT18, CUTA, KDM6A | KDM4E 69/4885F13A1 719/4885SMN1; SMN2 3816/4885 |
| US-20100254924-A1 | METHODS AND KITS FOR MAINTAINING THE CONDITION OF COLORED HAIR | CUTA, CYP11A1, TYR | KDM4E 648/4885F13A1 4054/4885SMN1; SMN2 4167/4885 |
| US-20100233114-A1 | METHODS OF STYLING HAIR | KRT18, SUCLG1, PIK3C3 | KDM4E 607/4885F13A1 517/4885SMN1; SMN2 4286/4885 |
| US-20210332055-A1 | TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS | ADORA2A, ADORA1, ADORA3 | KDM4E 3952/4885F13A1 2447/4885SMN1; SMN2 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.