Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402997 | 0.86 | PRMT5 (0.46) | CYP17A1PSMB8CD274HDAC1HDAC3 | |
| SCHEMBL90904 | 0.77 | AAK1 (0.39) | CYP17A1PRMT5WDR77AAK1 | |
| SCHEMBL879085 | 0.75 | AAK1 (0.38) | PRKDCPRMT5WDR77AAK1 | |
| SCHEMBL12316014 | 0.75 | NAMPT (0.39) | CYP17A1PSMB8MAP4K4PRMT5WDR77 | |
| SCHEMBL408034 | 0.72 | CYP17A1 (0.46) | CYP17A1PSMB8CD274HDAC1HDAC3 | |
| SCHEMBL12888644 | 0.71 | TSHR (0.36) | PSMB8PRMT5WDR77AAK1 | |
| SCHEMBL15184583 | 0.70 | AAK1 (0.51) | PRMT5WDR77AAK1 | |
| SCHEMBL13622824 | 0.70 | SMN1; SMN2 (0.42) | BRD4 | |
| SCHEMBL1255934 | 0.70 | AAK1 (0.54) | CYP17A1PSMB8PRMT5WDR77AAK1 | |
| SCHEMBL10382417 | 0.69 | ALDH1A1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120013245-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120013245-A1 | ELECTROACTIVE MATERIALS | NAT1, ADRA1D, ADRA1B | CYP17A1 143/4885PSMB8 4174/4885CD274 1302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.