Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10071172 | 0.86 | CYP17A1 (0.39) | PRMT5WDR77AAK1CYP17A1PSMB8 | |
| SCHEMBL1255934 | 0.84 | AAK1 (0.54) | PRMT5WDR77AAK1CYP17A1PSMB8 | |
| SCHEMBL15184583 | 0.83 | AAK1 (0.51) | PRMT5WDR77AAK1HIF1ACA1 | |
| SCHEMBL12567525 | 0.80 | AAK1 (0.48) | PRMT5WDR77AAK1PDGFRBKDR | |
| SCHEMBL27168078 | 0.78 | LPL (0.53) | PRMT5WDR77AAK1CYP17A1CA1 | |
| SCHEMBL22570942 | 0.77 | CYP17A1 (0.48) | PRMT5WDR77AAK1CYP17A1PDGFRB | |
| SCHEMBL29895473 | 0.77 | PRMT5 (0.47) | PRMT5WDR77AAK1CYP17A1HIF1A | |
| SCHEMBL1300326 | 0.77 | PRMT5 (0.47) | PRMT5WDR77AAK1CYP17A1HIF1A | |
| SCHEMBL408034 | 0.77 | CYP17A1 (0.46) | CYP17A1PSMB8CD274HDAC3HDAC1 | |
| SCHEMBL21318698 | 0.76 | AAK1 (0.46) | PRMT5WDR77AAK1CYP17A1PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10199577-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2019-02-05 | — | — | US | disclosed |
| US-20170040539-A1 | ELECTROACTIVE MATERIALS | LG CHEM, LTD. (KR) | 2017-02-09 | — | — | US | disclosed |
| US-20170040539-A1 | ELECTROACTIVE MATERIALS | LG CHEM, LTD. (KR) | 2017-02-09 | — | — | US | disclosed |
| US-9515267-B2 | Electroactive materials | EI DU PONT DE NEMOURS AND COMPANY (US) | 2016-12-06 | — | — | US | disclosed |
| US-9515267-B2 | Electroactive materials | EI DU PONT DE NEMOURS AND COMPANY (US) | 2016-12-06 | — | — | US | disclosed |
| US-9159927-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-10-13 | — | — | US | disclosed |
| US-9159927-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-10-13 | — | — | US | disclosed |
| US-8889269-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-11-18 | — | — | US | disclosed |
| US-8889269-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-11-18 | — | — | US | disclosed |
| US-8652655-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-18 | — | — | US | disclosed |
| US-20130087779-A1 | PROCESS AND MATERIALS FOR MAKING CONTAINED LAYERS AND DEVICES MADE WITH SAME | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130082251-A1 | ELECTROACTIVE MATERIALS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-04-04 | — | — | US | disclosed |
| US-20130082251-A1 | ELECTROACTIVE MATERIALS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-04-04 | — | — | US | disclosed |
| US-20120065432-A1 | ELECTROACTIVE MATERIALS | E.I DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120065432-A1 | ELECTROACTIVE MATERIALS | E.I DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120013245-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-19 | — | — | US | disclosed |
| US-8063399-B2 | Electroactive materials | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| US-8063399-B2 | Electroactive materials | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| US-20110095269-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY | 2011-04-28 | — | — | US | disclosed |
| US-20110095269-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120013245-A1 | ELECTROACTIVE MATERIALS | NAT1, ADRA1D, ADRA1B | PRMT5 2035/4885WDR77 3410/4885AAK1 1774/4885 |
| US-20120065432-A1 | ELECTROACTIVE MATERIALS | NAT1, ADRA1D, ADRA1B | PRMT5 2035/4885WDR77 3410/4885AAK1 1774/4885 |
| US-20110095269-A1 | ELECTROACTIVE MATERIALS | NAT1, ADRA1D, ADRA1B | PRMT5 2035/4885WDR77 3410/4885AAK1 1774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.