Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10075505 | 0.91 | SLC6A4 (0.44) | KMT2ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL10041961 | 0.91 | SLC6A4 (0.44) | KMT2ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL10071230 | 0.83 | MEN1 (0.40) | KMT2AALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10071834 | 0.77 | MEN1 (0.42) | KMT2AALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6809831 | 0.76 | SLC6A2 (0.48) | KMT2ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL20340489 | 0.74 | SLC6A2 (0.40) | KMT2ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL10041953 | 0.74 | SLC6A2 (0.40) | KMT2ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL20436755 | 0.74 | SLC6A2 (0.40) | KMT2ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL15491044 | 0.74 | SLC6A2 (0.40) | KMT2ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL12609484 | 0.73 | KDM4E (0.42) | KMT2AALDH1A1MEN1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095106-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | SUNOVION PHARMACEUTICALS INC. (US) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095106-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | PNMT, ALKBH5, ALKBH2 | KMT2A 388/4885ALDH1A1 501/4885SLC6A2 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.