Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 4/20 | 0.31 |
| ▸ | KDR | P35968 | 3/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | YES1 | P07947 | 1/20 | 0.30 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.30 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.30 |
| ▸ | LTK | P29376 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | MST1R | Q04912 | 1/20 | 0.30 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13785392 | 0.91 | SCN9A (0.33) | SCN9AABL1ALDH1A1F2GLA | |
| SCHEMBL3730552 | 0.91 | SCN9A (0.39) | SCN9AABL1ALDH1A1F2GLA | |
| SCHEMBL155250 | 0.89 | SCN9A (0.33) | SCN9AABL1ALDH1A1F2GLA | |
| SCHEMBL632771 | 0.88 | HPGDS (0.36) | SCN9AALDH1A1F2GLAHPGD | |
| SCHEMBL13785404 | 0.88 | PARP1 (0.34) | SCN9AABL1ALDH1A1F2GLA | |
| SCHEMBL2865535 | 0.88 | ALDH1A1 (0.35) | SCN9AALDH1A1F2GLAHPGD | |
| SCHEMBL13785391 | 0.87 | MET (0.32) | SCN9AALDH1A1F2GLAHPGD | |
| SCHEMBL633067 | 0.87 | SCN9A (0.35) | SCN9AALDH1A1F2GLAHPGD | |
| SCHEMBL13077475 | 0.87 | SCD (0.30) | — | |
| SCHEMBL3727686 | 0.87 | RAB9A (0.35) | SCN9AALDH1A1F2GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231614-B1 | Quinoline derivatives and their use as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2012-02-22 | — | — | EP | disclosed |
| WO-2009087098-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-16 | — | — | WO | disclosed |