SCHEMBL10071739

SCHEMBL10071739

CCc1ccc2c(c1)c(=O)c1ccccc1n2C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.54
NPC1 O15118 5/20 0.52
RAB9A P51151 5/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
PGR P06401 1/20 0.52
RORA P35398 1/20 0.52
RORC P51449 1/20 0.52
RORB Q92753 1/20 0.52
ALDH1A1 P00352 4/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
HCRTR1 O43613 2/20 0.50
GPR3 P46089 1/20 0.47
KDM4E B2RXH2 3/20 0.47
HPGD P15428 3/20 0.47
HSD17B10 Q99714 3/20 0.47
MAPT P10636 2/20 0.46
HTT P42858 2/20 0.46
P2RX4 Q99571 1/20 0.46
TLR9 Q9NR96 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13951372 0.90 ATM (0.62) ATMNPC1RAB9AMEN1KMT2A
SCHEMBL2604391 0.86 GPR3 (0.59) MEN1KMT2APGRRORARORC
SCHEMBL13226089 0.86 ALDH1A1 (0.72) MEN1KMT2APGRRORARORC
SCHEMBL18535741 0.83 ALDH1A1 (0.54) PGRRORARORCRORBALDH1A1
SCHEMBL8086611 0.83 KDM4E (0.49) ATMPGRRORARORCRORB
SCHEMBL14280396 0.83 RORA (0.62) ATMNPC1RAB9AMEN1KMT2A
SCHEMBL25752332 0.81 ATM (0.46) ATMNPC1RAB9AMEN1KMT2A
SCHEMBL13226088 0.81 ATM (0.48) ATMNPC1RAB9AMEN1KMT2A
SCHEMBL29361718 0.81 ATM (0.71) ATMNPC1RAB9AMEN1KMT2A
SCHEMBL85776 0.81 ATM (0.71) ATMNPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092872-B2 Optical film, antireflection film, and polarizing plate and display device using the same FUJIFILM CORPORATION (JP) 2012-01-10 US disclosed
US-8092872-B2 Optical film, antireflection film, and polarizing plate and display device using the same FUJIFILM CORPORATION (JP) 2012-01-10 US disclosed
US-7785676-B2 Optical compensation sheet, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-08-31 US disclosed
US-7785676-B2 Optical compensation sheet, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-08-31 US disclosed
US-20090122233-A1 OPTICAL COMPENSATION SHEET, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-05-14 US disclosed
US-20090122233-A1 OPTICAL COMPENSATION SHEET, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-05-14 US disclosed
US-20080131674-A1 OPTICAL FILM, ANTIREFLECTION FILM, AND POLARIZING PLATE AND DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2008-06-05 US disclosed
US-20080131674-A1 OPTICAL FILM, ANTIREFLECTION FILM, AND POLARIZING PLATE AND DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2008-06-05 US disclosed
WO-2007049814-A1 OPTICAL COMPENSATION SHEET, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-05-03 WO disclosed