Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL27947517 | 0.84 | HRH4 (0.33) | OR51E2 | |
| Trifluoroacetamide SCHEMBL15993978 | 0.80 | LMNA (0.50) | ALDH1A1LMNAOR51E2TDP1 | |
| Trifluoroacetamide SCHEMBL20137335 | 0.77 | HDAC6 (0.35) | ALDH1A1LMNAOR51E2TDP1 | |
| Trifluoroacetamide SCHEMBL28877296 | 0.77 | HDAC6 (0.35) | ALDH1A1LMNAOR51E2TDP1 | |
| Trifluoroacetamide SCHEMBL15993858 | 0.76 | LMNA (0.46) | ALDH1A1LMNAOR51E2TDP1 | |
| Trifluoroacetamide SCHEMBL8526109 | 0.76 | — | — | |
| Trifluoroacetamide SCHEMBL142 | 0.76 | — | — | |
| Trifluoroacetamide SCHEMBL27678123 | 0.76 | LMNA (0.42) | ALDH1A1LMNAOR51E2TDP1 | |
| Trifluoroacetamide SCHEMBL11793075 | 0.73 | — | — | |
| Trifluoroacetamide SCHEMBL5638451 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9803240-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| EP-2757091-B1 | Stabilized Nucleic Acid Dark Quencher-Fluorophore Probes | BIOSEARCH TECH INC (US) | 2017-06-28 | — | — | EP | disclosed |
| EP-2757091-A1 | Stabilized Nucleic Acid Dark Quencher-Fluorophore Probes | Biosearch Technologies, Inc. (US) | 2014-07-23 | — | — | EP | disclosed |
| US-20140194611-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-8674094-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2014-03-18 | — | — | US | disclosed |
| CN-102037144-B | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES INC | 2013-09-25 | — | — | CN | disclosed |
| US-8466266-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-20110282041-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2011-11-17 | — | — | US | disclosed |
| CN-102037144-A | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES INC | 2011-04-27 | — | — | CN | disclosed |
| EP-2268608-A2 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | Biosearch Technologies, Inc. (US) | 2011-01-05 | — | — | EP | disclosed |
| US-20090259030-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES (US) | 2009-10-15 | — | — | US | disclosed |
| WO-2009124150-A2 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259030-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | DDX1, DDX18, DDX3X | ALDH1A1 1107/4885LMNA 417/4885OR51E2 1305/4885 |
| US-20110282041-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | DDX1, DDX18, DDX3X | ALDH1A1 1107/4885LMNA 417/4885OR51E2 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.