Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 14/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45989 | 0.78 | — | — | |
| SCHEMBL10072372 | 0.76 | HCRTR1 (0.38) | OPRM1OPRK1HCRTR1 | |
| SCHEMBL10072374 | 0.69 | HCRTR1 (0.42) | OPRM1OPRK1HCRTR1 | |
| SCHEMBL12826657 | 0.68 | HCRTR1 (0.41) | OPRM1OPRK1HCRTR1 | |
| SCHEMBL13333413 | 0.64 | OPRM1 (0.35) | OPRM1OPRK1HCRTR1 | |
| SCHEMBL12609249 | 0.64 | OPRM1 (0.35) | OPRM1OPRK1HCRTR1 | |
| SCHEMBL18473485 | 0.63 | HCRTR1 (0.39) | OPRM1OPRK1HCRTR1 | |
| SCHEMBL18473483 | 0.63 | HCRTR1 (0.46) | OPRM1OPRK1HCRTR1 | |
| SCHEMBL12945205 | 0.62 | HCRTR1 (0.38) | OPRM1OPRK1HCRTR1 | |
| SCHEMBL18473622 | 0.62 | HCRTR1 (0.40) | OPRM1OPRK1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010412-A1 | Process for the Synthesis of Substituted Morphinans | ALKERMES, INC. (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010412-A1 | Process for the Synthesis of Substituted Morphinans | CYP1B1, DHPS, CYP4B1 | OPRM1 251/4885OPRK1 655/4885HCRTR1 3605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.