Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 8/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45987 | 0.77 | MAOA (0.31) | OPRM1OPRK1 | |
| SCHEMBL12826657 | 0.77 | HCRTR1 (0.41) | HCRTR1OPRM1OPRK1 | |
| SCHEMBL10072367 | 0.76 | OPRM1 (0.38) | HCRTR1OPRM1OPRK1 | |
| SCHEMBL11888556 | 0.71 | MAOA (0.32) | OPRM1OPRK1 | |
| SCHEMBL18473622 | 0.71 | HCRTR1 (0.40) | HCRTR1OPRM1OPRK1 | |
| SCHEMBL12830845 | 0.67 | MAOA (0.33) | OPRM1 | |
| SCHEMBL13973662 | 0.66 | HCRTR1 (0.34) | HCRTR1OPRM1 | |
| SCHEMBL20170680 | 0.66 | HCRTR1 (0.38) | HCRTR1OPRM1OPRK1 | |
| SCHEMBL16131233 | 0.65 | OPRM1 (0.43) | OPRM1OPRK1 | |
| SCHEMBL17552919 | 0.65 | OPRM1 (0.43) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010412-A1 | Process for the Synthesis of Substituted Morphinans | ALKERMES, INC. (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010412-A1 | Process for the Synthesis of Substituted Morphinans | CYP1B1, DHPS, CYP4B1 | HCRTR1 3605/4885OPRM1 251/4885OPRK1 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.