Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12945205 | 0.68 | HCRTR1 (0.38) | OPRM1OPRD1OPRK1HCRTR1 | |
| SCHEMBL13333565 | 0.68 | OPRM1 (0.33) | OPRM1OPRD1OPRK1HCRTR1 | |
| SCHEMBL12945079 | 0.67 | HCRTR1 (0.44) | OPRM1OPRD1OPRK1HCRTR1 | |
| SCHEMBL13333413 | 0.67 | OPRM1 (0.35) | OPRM1OPRD1OPRK1HCRTR1 | |
| SCHEMBL10072367 | 0.64 | OPRM1 (0.38) | OPRM1OPRK1HCRTR1 | |
| SCHEMBL19669797 | 0.64 | OPRM1 (0.40) | OPRM1OPRD1OPRK1 | |
| SCHEMBL19669810 | 0.61 | OPRM1 (0.42) | OPRM1OPRD1OPRK1 | |
| SCHEMBL18473622 | 0.61 | HCRTR1 (0.40) | OPRM1OPRD1OPRK1HCRTR1 | |
| SCHEMBL10072372 | 0.61 | HCRTR1 (0.38) | OPRM1OPRK1HCRTR1 | |
| SCHEMBL10072374 | 0.60 | HCRTR1 (0.42) | OPRM1OPRK1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152527-A1 | PROCESS FOR THE PREPARATION OF MORPHINE ANALOGUES | SUN PHARMACEUTICAL INDUSTRIES LTD. (IN) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152527-A1 | PROCESS FOR THE PREPARATION OF MORPHINE ANALOGUES | OPRM1, OPRK1, OPRD1 | OPRM1 1/4885OPRD1 3/4885OPRK1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.