SCHEMBL10072400

SCHEMBL10072400

OC(COc1ccccc1)COc1cccc(OCC(O)COc2ccccc2)c1

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
HIF1A Q16665 2/20 0.61
MAPK1 P28482 2/20 0.61
LMNA P02545 2/20 0.59
SMN1; SMN2 Q16637 3/20 0.57
CYP2D6 P10635 3/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
ADRB2 P07550 1/20 0.56
ADRB1 P08588 1/20 0.56
ADRB3 P13945 1/20 0.56
KDM4E B2RXH2 2/20 0.56
ACE2 Q9BYF1 1/20 0.56
MAPT P10636 2/20 0.53
HTT P42858 1/20 0.53
RECQL P46063 1/20 0.53
GAA P10253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14546244 0.93 TSHR (0.54) TSHRHIF1AMAPK1LMNASMN1; SMN2
SCHEMBL6940631 0.93 HTR1D (0.56) TSHRHIF1AMAPK1LMNASMN1; SMN2
SCHEMBL267463 0.91 LMNA (0.68) TSHRHIF1ALMNASMN1; SMN2CYP2D6
SCHEMBL14546242 0.91 KDM1A (0.55) TSHRHIF1AMAPK1LMNASMN1; SMN2
SCHEMBL2720404 0.88 MAPK1 (0.50) TSHRHIF1AMAPK1LMNASMN1; SMN2
SCHEMBL13853182 0.88 TSHR (0.50) TSHRHIF1AMAPK1LMNASMN1; SMN2
SCHEMBL13853173 0.87 KDM1A (0.51) TSHRHIF1AMAPK1LMNASMN1; SMN2
SCHEMBL11400908 0.85 LMNA (0.61) TSHRHIF1ALMNASMN1; SMN2CYP2D6
SCHEMBL14546417 0.85 KDM1A (0.58) TSHRHIF1AMAPK1SMN1; SMN2KDM4E
SCHEMBL11888312 0.84 MAPK1 (0.67) TSHRHIF1AMAPK1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023209463-A1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-11-02 WO disclosed
EP-2670375-B1 DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2019-05-01 EP disclosed
US-9295617-B2 Dental composition, method of producing and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-03-29 US disclosed
US-9295617-B2 Dental composition, method of producing and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-03-29 US disclosed
US-8710113-B2 Dental composition, kit of parts and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-04-29 US disclosed
US-8710113-B2 Dental composition, kit of parts and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-04-29 US disclosed
US-20130303655-A1 DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-11-14 US disclosed
US-20130303655-A1 DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-11-14 US disclosed
US-20130109777-A1 DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-05-02 US disclosed
US-20130109777-A1 DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-05-02 US disclosed
EP-2481390-A1 Dental composition, method of producing and use thereof 3M Innovative Properties Company (US) 2012-08-01 EP disclosed
WO-2012003136-A1 DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-01-05 WO disclosed
EP-2401998-A1 Dental composition, kit of parts and use thereof 3M Innovative Properties Company (US) 2012-01-04 EP disclosed
EP-0022073-B1 DIGLYCIDYL ETHERS OF DI-SECONDARY ALCOHOLS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1985-01-30 EP disclosed
US-4284574-A MOLDING MATERIALS CIBA-GEIGY CORPORATION (US) 1981-08-18 US disclosed
EP-0022073-A1 Diglycidyl ethers of di-secondary alcohols, their preparation and their use CIBA-GEIGY AG (CH) 1981-01-07 EP disclosed
US-4175173-A Powder coating compositions containing an epoxide resin and an acid hardener CIBA-GEIGY CORPORATION (US) 1979-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130303655-A1 DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF PAM, PTMS, ACR TSHR 3551/4885HIF1A 1518/4885MAPK1 4208/4885
US-20130109777-A1 DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF KIT, KDM5C, PHAX TSHR 4041/4885HIF1A 1229/4885MAPK1 2853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.