SCHEMBL2720404

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10072289	0.92	LMNA (0.52)	TSHRHIF1ASMN1; SMN2LMNAKDM4E
	SCHEMBL14904491	0.88	PLA2G4B (0.53)	MAPK1TSHRHIF1AKDM4E
	SCHEMBL10072400	0.88	TSHR (0.61)	MAPK1TSHRHIF1ASMN1; SMN2LMNA
	SCHEMBL14904485	0.86	KCNA3 (0.50)	SMN1; SMN2LMNAKDM4EL3MBTL1CYP2D6
	SCHEMBL2721719	0.84	LMNA (0.42)	MAPK1TSHRHIF1ALMNAKDM4E
	SCHEMBL11400908	0.82	LMNA (0.61)	TSHRHIF1ASMN1; SMN2LMNAKDM4E
	SCHEMBL12222360	0.82	LMNA (0.53)	MAPK1TSHRHIF1ASMN1; SMN2LMNA
	SCHEMBL10713338	0.82	RECQL (0.53)	TSHRHIF1ASMN1; SMN2LMNAKDM4E
	SCHEMBL10711050	0.82	RECQL (0.53)	TSHRHIF1ASMN1; SMN2LMNAKDM4E
	SCHEMBL10710354	0.81	RECQL (0.57)	TSHRHIF1ASMN1; SMN2LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.