SCHEMBL10072418

SCHEMBL10072418

Cc1ccc2c(c1)N(c1ccccc1)c1ccccc1CC2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.45
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
GAA P10253 3/20 0.40
GFER P55789 1/20 0.40
ALDH1A1 P00352 4/20 0.40
KMT2A Q03164 5/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 4/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HSD17B3 P37058 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPK1 P28482 1/20 0.38
UBE2N P61088 1/20 0.38
DRD2 P14416 1/20 0.37
DRD4 P21917 1/20 0.37
DRD3 P35462 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12901974 0.90 HPGD (0.53) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL14155275 0.90 HPGD (0.45) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL11978686 0.84 KMT2A (0.47) HPGDGAAKMT2ANPC1RAB9A
SCHEMBL12559590 0.84 L3MBTL1 (0.54) HPGDGAAGFERALDH1A1KMT2A
SCHEMBL14281334 0.84 HPGD (0.59) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL12952460 0.80 GNG2 (0.46) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL1102472 0.80 HPGD (0.41) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL13443081 0.78 ALDH1A1 (0.43) HPGDADRA2AADRA2BADRA2CGAA
SCHEMBL11978695 0.78 ALDH1A1 (0.41) HPGDGAAALDH1A1KMT2ANPC1
SCHEMBL12992625 0.78 HPGD (0.50) HPGDADRA2AADRA2BADRA2CGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-7888863-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2011-02-15 US disclosed
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same GRACEL DISPLAY INC. (KR) 2010-04-22 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed
EP-2112214-A1 Dibenzo[g,p]chrysene derivatives and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-10-28 EP disclosed
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-22 US disclosed
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, FZD7 HPGD 2654/4885ADRA2A 3343/4885ADRA2B 2756/4885
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same OCIAD1, OR10J3, ORMDL3 HPGD 785/4885ADRA2A 2264/4885ADRA2B 2041/4885
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OXER1, L1CAM, RPL41 HPGD 4341/4885ADRA2A 1205/4885ADRA2B 797/4885
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 HPGD 1011/4885ADRA2A 3086/4885ADRA2B 2936/4885
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 HPGD 2787/4885ADRA2A 2843/4885ADRA2B 2389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.