Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688169 | 0.85 | CXCR2 (0.47) | ALDH1A1LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL688365 | 0.76 | PTGS2 (0.44) | ALDH1A1LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL688675 | 0.75 | LMNA (0.45) | ALDH1A1LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL575717 | 0.70 | CA2 (0.46) | HTTKMT2ACA1CA2MMP2 | |
| SCHEMBL687288 | 0.67 | CXCR2 (0.44) | ALDH1A1HPGDALOX15HTTUSP2 | |
| SCHEMBL12239572 | 0.66 | CXCR2 (0.70) | KMT2ACXCR2CA1CA2GAA | |
| SCHEMBL13104029 | 0.65 | GRIA1 (0.58) | ALDH1A1LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL688163 | 0.64 | PTGS1 (0.54) | ALDH1A1LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL19454404 | 0.63 | ALDH1A1 (0.71) | ALDH1A1LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL687263 | 0.62 | CXCR2 (0.55) | LMNASMN1; SMN2HTTCXCR2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606248-B1 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE SPA (IT) | 2012-02-29 | — | — | EP | disclosed |