Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458496 | 0.92 | LMNA (0.40) | LMNAMAPTSMN1; SMN2HTR6CYP3A4 | |
| SCHEMBL458029 | 0.84 | ACHE (0.41) | LMNAMAPTSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL30018007 | 0.84 | ALDH1A1 (0.41) | LMNAMAPTSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL30017862 | 0.84 | ALDH1A1 (0.41) | LMNAMAPTSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL458412 | 0.84 | ALDH1A1 (0.41) | LMNAMAPTSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL28423522 | 0.81 | CYP1A1 (0.50) | MAPTSMN1; SMN2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL10073368 | 0.81 | CA12 (0.44) | LMNAMAPTCYP3A4ALDH1A1KDM4E | |
| SCHEMBL16005619 | 0.76 | CNR2 (0.41) | LMNACYP3A4ALDH1A1CYP2D6CA1 | |
| SCHEMBL4976814 | 0.75 | LMNA (0.43) | LMNAMAPTSMN1; SMN2HTR6CYP3A4 | |
| SCHEMBL28521698 | 0.74 | CA12 (0.48) | LMNAMAPTSMN1; SMN2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031358-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2012-03-15 | — | — | WO | disclosed |