SCHEMBL458412

SCHEMBL458412

COc1cc(OC)c(-c2c(OC)cc(OC)cc2P(c2cc(C)cc(C)c2)c2cc(C)cc(C)c2)c(P(c2cc(C)cc(C)c2)c2cc(C)cc(C)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 3/20 0.41
CYP1A2 P05177 2/20 0.41
CNR2 P34972 2/20 0.37
ACHE P22303 2/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
USP2 O75604 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NQO2 P16083 2/20 0.35
LMNA P02545 2/20 0.34
ELANE P08246 3/20 0.33
CYP19A1 P11511 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP2E1 P05181 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30017862 1.00 ALDH1A1 (0.41) ALDH1A1CYP3A4CYP1A2CNR2ACHE
SCHEMBL30018007 1.00 ALDH1A1 (0.41) ALDH1A1CYP3A4CYP1A2CNR2ACHE
SCHEMBL458029 0.86 ACHE (0.41) ALDH1A1CYP3A4CYP1A2ACHECA12
SCHEMBL29536408 0.85 CYP1A2 (0.38) ALDH1A1CYP3A4CYP1A2ACHECA12
SCHEMBL457923 0.85 CYP1A2 (0.38) ALDH1A1CYP3A4CYP1A2ACHECA12
SCHEMBL10073379 0.84 LMNA (0.36) ALDH1A1CYP3A4CYP1A2ACHECA12
SCHEMBL15119998 0.84 ALDH1A1 (0.33) ALDH1A1CYP3A4CYP1A2CYP1A1CYP1B1
SCHEMBL10073368 0.82 CA12 (0.44) ALDH1A1CYP3A4CYP1A2CA12CA1
SCHEMBL458496 0.81 LMNA (0.40) ALDH1A1CYP3A4CYP1A2CA12CA1
SCHEMBL31568878 0.79 ALDH1A1 (0.36) ALDH1A1CYP3A4CYP1A2ACHEUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192586-A1 GAS PHASE PROCESS FOR ACRYLATE PRODUCTION FROM ETHYLENE AND CARBON DIOXIDE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-06-22 US claimed
WO-2023114926-A1 GAS PHASE PROCESS FOR ACRYLATE PRODUCTION FROM ETHYLENE AND CARBON DIOXIDE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-06-22 WO claimed
US-11530177-B2 Formation of α,β-unsaturated carboxylic acids and salts thereof from metalalactones and anionic polyelectrolytes CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2022-12-20 US claimed
US-20210179525-A1 FORMATION OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2021-06-17 US claimed
US-10941101-B2 Formation of alpha,beta-unsaturated carboxylic acids and salts thereof from metalalactones and anionic polyelectrolytes CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2021-03-09 US claimed
US-20190345089-A1 FORMATION OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2019-11-14 US claimed
EP-4090654-B1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS LUPIN LTD (IN) 2025-07-09 EP disclosed
US-12344592-B2 Methods, processes and intermediates for preparing chroman compounds LUPIN LIMITED (IN) 2025-07-01 US disclosed
US-12162829-B2 Gas phase process for acrylate production from ethylene and carbon dioxide CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-12-10 US disclosed
EP-3634932-B1 HIGH POROSITY AROMATIC RESINS AS PROMOTERS IN ACRYLATE PRODUCTION FROM COUPLING REACTIONS OF OLEFINS AND CARBON DIOXIDE CHEVRON PHILLIPS CHEMICAL CO LP (US) 2024-07-24 EP disclosed
CN-114981253-B Process and intermediates for preparing chroman compounds and methods therefor 印度鲁宾有限公司 2024-06-18 CN disclosed
EP-3995492-B1 A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES SpecGx LLC (US) 2024-05-29 EP disclosed
EP-3860970-B1 EFFECTS OF CATALYST CONCENTRATION AND SOLID ACTIVATOR ON NICKEL-MEDIATED OLEFIN/CARBON DIOXIDE COUPLING TO ACRYLATES CHEVRON PHILLIPS CHEMICAL CO LP (US) 2023-08-09 EP disclosed
WO-2016007823-A1 PROCESS FOR PREPARING SUBSTITUTED PHENYLALKANES MALLINCKRODT LLC (US) 2016-01-14 WO disclosed
US-20150329652-A1 Synthesis of Aryl Coupled BIS Phenoxides and Their Use in Olefin Polymerization Catalyst Systems With Activator-Supports CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-11-19 US disclosed
WO-2015175636-A1 SYNTHESIS OF ARYL COUPLED BIS PHENOXIDES AND THEIR USE IN OLEFIN POLYMERIZATION CATALYST SYSTEMS WITH ACTIVATOR-SUPPORTS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-11-19 WO disclosed
US-9062085-B2 Biaryl diphosphine ligands, intermediates of the same and their use in asymmetric catalysis KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2015-06-23 US disclosed
US-20130184479-A1 BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2013-07-18 US disclosed
EP-2614069-A1 BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS Kanata Chemical Technologies Inc. (CA) 2013-07-17 EP disclosed
WO-2012031358-A1 BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2012-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345089-A1 FORMATION OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES ALOX12, ME1, RARA ALDH1A1 338/4885CYP3A4 2443/4885CYP1A2 2176/4885
US-12162829-B2 Gas phase process for acrylate production from ethylene and carbon dioxide MSMO1, ALOX15, ALOX12 ALDH1A1 1885/4885CYP3A4 1550/4885CYP1A2 1463/4885
US-10941101-B2 Formation of alpha,beta-unsaturated carboxylic acids and salts thereof from metalalactones and anionic polyelectrolytes ALOX12, ME1, RARA ALDH1A1 338/4885CYP3A4 2443/4885CYP1A2 2176/4885
US-20210179525-A1 FORMATION OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES ME1, DEGS1, ACSL1 ALDH1A1 353/4885CYP3A4 2066/4885CYP1A2 2319/4885
US-11530177-B2 Formation of α,β-unsaturated carboxylic acids and salts thereof from metalalactones and anionic polyelectrolytes ME1, ACSL1, ALOX12 ALDH1A1 344/4885CYP3A4 2100/4885CYP1A2 2363/4885
US-20230192586-A1 GAS PHASE PROCESS FOR ACRYLATE PRODUCTION FROM ETHYLENE AND CARBON DIOXIDE MSMO1, ALOX15, ALOX12 ALDH1A1 1885/4885CYP3A4 1550/4885CYP1A2 1463/4885
US-20130184479-A1 BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS AGPS, COASY, BLVRB ALDH1A1 1187/4885CYP3A4 121/4885CYP1A2 57/4885
US-12344592-B2 Methods, processes and intermediates for preparing chroman compounds CASR, CALCR, RYR1 ALDH1A1 2602/4885CYP3A4 368/4885CYP1A2 1366/4885
US-20150329652-A1 Synthesis of Aryl Coupled BIS Phenoxides and Their Use in Olefin Polymerization Catalyst Systems With Activator-Supports PPOX, AOC2, AOC3 ALDH1A1 1691/4885CYP3A4 74/4885CYP1A2 137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.