Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.54 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 3/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17287421 | 0.91 | PPID (0.54) | PPIDGPR142MMP8MEN1KMT2A | |
| SCHEMBL2896038 | 0.90 | MEN1 (0.57) | PPIDGPR142MMP8L3MBTL1MEN1 | |
| SCHEMBL2896037 | 0.90 | MEN1 (0.57) | PPIDGPR142MMP8L3MBTL1MEN1 | |
| SCHEMBL22424808 | 0.87 | ALDH1A1 (0.51) | L3MBTL1MME | |
| SCHEMBL10662173 | 0.85 | MME (0.58) | GPR142LTA4HMMEACECPA1 | |
| SCHEMBL7428724 | 0.85 | ITGA4 (0.59) | PPIDGPR142MMP8MEN1KMT2A | |
| SCHEMBL7428720 | 0.85 | ITGA4 (0.59) | PPIDGPR142MMP8MEN1KMT2A | |
| SCHEMBL9554934 | 0.85 | PPID (0.56) | PPIDGPR142MMP8LTA4H | |
| SCHEMBL9185848 | 0.84 | SIGMAR1 (0.56) | PPIDMMP8LTA4HRAB9A | |
| SCHEMBL31289371 | 0.83 | MME (0.49) | L3MBTL1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093274-B2 | Inhibitors of protein prenyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-10 | — | — | US | disclosed |
| US-20100063114-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063114-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | GGT1, FNTA, FNTB | PPID 2016/4885GPR142 3237/4885MMP8 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.