Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587685 | 0.95 | GAA (0.47) | GAATSHRTDP1RAB9ASMPD1 | |
| SCHEMBL16125662 | 0.87 | HCAR2 (0.46) | TSHRRAB9A | |
| SCHEMBL12367978 | 0.87 | HCAR2 (0.46) | TSHRRAB9A | |
| SCHEMBL29316074 | 0.85 | MMP13 (0.47) | MMP3MMP2TSHRMMP13MMP12 | |
| SCHEMBL29321446 | 0.83 | TSHR (0.48) | MMP3MMP2TSHRMMP13MMP12 | |
| SCHEMBL29316079 | 0.82 | TSHR (0.50) | MMP3MMP2TSHRMMP13MMP12 | |
| SCHEMBL2556244 | 0.82 | HCAR2 (0.50) | TSHRTDP1 | |
| SCHEMBL2619036 | 0.81 | TSHR (0.52) | MMP3MMP2TSHRMMP13MMP12 | |
| SCHEMBL21389608 | 0.81 | TSHR (0.52) | MMP3MMP2TSHRMMP13MMP12 | |
| SCHEMBL13220802 | 0.81 | TSHR (0.52) | MMP3MMP2TSHRMMP13MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361908-B2 | Modified surface material, method for preparing same and uses thereof | UNIVERSITE PARIS 7-DENIS DIDEROT (FR) | 2013-01-29 | — | — | US | disclosed |
| US-20120015138-A1 | MODIFIED SURFACE MATERIAL, METHOD FOR PREPARING SAME AND USES THEREOF | ALCHIMEDICS (FR) | 2012-01-19 | — | — | US | disclosed |
| US-8053567-B2 | forming undercoatings on semiconductor by polymerizing monomers with diazonium salt which can electrochemical reduction having a polymerization initiator function; in situ free radical polymerization; stents, implants, prostheses; corrosion resistance | Universite Paris 7—Denis Diderot (FR) | 2011-11-08 | — | — | US | disclosed |
| EP-1778770-B1 | MODIFIED SURFACE MATERIAL, METHOD FOR PREPARING SAME AND USES THEREOF | UNIV PARIS 7 DENIS DIDEROT (FR) | 2011-11-02 | — | — | EP | disclosed |
| US-20080064783-A1 | Modified Surface Material, Method for Preparing Same and Uses Thereof | ALCHIMEDICS (FR) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064783-A1 | Modified Surface Material, Method for Preparing Same and Uses Thereof | SOAT2, SOAT1, INMT | MMP3 4306/4885GAA 2217/4885MMP2 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.