Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 20/20 | 0.44 |
| ▸ | MAOA | P21397 | 19/20 | 0.44 |
| ▸ | MAOB | P27338 | 19/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073893 | 0.76 | LMNA (0.43) | KDM1A | |
| SCHEMBL10073886 | 0.69 | KDM1A (0.53) | KDM1AMAOAMAOB | |
| SCHEMBL10073913 | 0.67 | KDM1A (0.55) | KDM1AMAOAMAOB | |
| SCHEMBL10073914 | 0.66 | RORC (0.40) | KDM1AMAOAMAOB | |
| SCHEMBL4331068 | 0.65 | KDM1A (0.67) | KDM1AMAOAMAOB | |
| Ammonia Solution, Strong SCHEMBL11017865 | 0.63 | KDM1A (0.64) | KDM1AMAOAMAOB | |
| SCHEMBL10573931 | 0.63 | KDM1A (0.57) | KDM1AMAOAMAOB | |
| SCHEMBL11054309 | 0.63 | KDM1A (0.57) | KDM1AMAOAMAOB | |
| SCHEMBL10573928 | 0.63 | KDM1A (0.57) | KDM1AMAOAMAOB | |
| SCHEMBL23465403 | 0.62 | KDM1A (1.00) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046455-A1 | Catalytic Cyclopropanation of Alkenes with Alpha-Cyano-Diazoacetates | NATIONAL SCIENCE FOUNDATION | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046455-A1 | Catalytic Cyclopropanation of Alkenes with Alpha-Cyano-Diazoacetates | PPOX, POR, PCCA | KDM1A 2149/4885MAOA 173/4885MAOB 444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.