Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | DNTT | P04053 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073917 | 0.94 | SPHK1 (0.36) | SPHK1ALDH1A1CPB2GPR119 | |
| SCHEMBL29187859 | 0.88 | CYP4F2 (0.41) | SPHK1CPB2EPHX2GPR119 | |
| SCHEMBL29187860 | 0.88 | CYP4F2 (0.41) | SPHK1CPB2EPHX2GPR119 | |
| SCHEMBL30158917 | 0.88 | CYP4F2 (0.41) | SPHK1CPB2EPHX2GPR119 | |
| SCHEMBL30159122 | 0.84 | ALOX5 (0.33) | ALOX5ALDH1A1POLBL3MBTL1CPB2 | |
| SCHEMBL13123340 | 0.80 | NR1H2 (0.33) | SPHK1EPHX2 | |
| SCHEMBL12033287 | 0.80 | NR1H2 (0.33) | SPHK1EPHX2 | |
| SCHEMBL13642174 | 0.80 | ALDH1A1 (0.39) | ALOX5ALDH1A1POLBL3MBTL1CPB2 | |
| SCHEMBL29188007 | 0.77 | NR1H2 (0.39) | EPHX2 | |
| SCHEMBL29188005 | 0.77 | NR1H2 (0.39) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046455-A1 | Catalytic Cyclopropanation of Alkenes with Alpha-Cyano-Diazoacetates | NATIONAL SCIENCE FOUNDATION | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046455-A1 | Catalytic Cyclopropanation of Alkenes with Alpha-Cyano-Diazoacetates | PPOX, POR, PCCA | SPHK1 3516/4885ALOX5 1404/4885ALDH1A1 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.