Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 5/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 4/20 | 0.45 |
| ▸ | CASP7 | P55210 | 3/20 | 0.45 |
| ▸ | CASP6 | P55212 | 2/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.45 |
| ▸ | CASP9 | P55211 | 2/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626800 | 1.00 | CASP3 (0.49) | CASP3SYKCTSKCTSBCASP1 | |
| SCHEMBL4422741 | 1.00 | CASP3 (0.49) | CASP3SYKCTSKCTSBCASP1 | |
| SCHEMBL7381224 | 0.91 | CASP3 (0.53) | CASP3CTSKCTSBCASP1CASP7 | |
| SCHEMBL17261861 | 0.90 | CTSK (0.52) | SYKCTSKCTSBCASP1CTSL | |
| SCHEMBL79538 | 0.90 | CASP1 (0.54) | SYKCTSKCTSBCASP1CTSL | |
| SCHEMBL79537 | 0.90 | CASP1 (0.54) | SYKCTSKCTSBCASP1CTSL | |
| SCHEMBL8414721 | 0.89 | CASP3 (0.52) | CASP3SYKCTSKCTSBCTSD | |
| SCHEMBL7902746 | 0.89 | CASP3 (0.51) | CASP3CTSKCTSBCASP1CASP7 | |
| SCHEMBL27544004 | 0.88 | CASP3 (0.59) | CASP3CASP1CASP7CASP8CASP9 | |
| SCHEMBL27544008 | 0.88 | CASP3 (0.59) | CASP3CASP1CASP7CASP8CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021800-A2 | CASPASE INHIBITORS AS THERAPEUTICS FOR NEURAL AND ORGAN INJURY AND IMAGING | BANYAN BIOMARKERS (US) | 2012-02-16 | — | — | WO | disclosed |