Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | CTSD | P07339 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | KYNU | Q16719 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411381 | 0.91 | CASP3 (0.55) | CASP3CTSDCTSKCTSBREN | |
| SCHEMBL19694834 | 0.89 | KYNU (0.56) | CTSKKYNUSYKCTSBKLK5 | |
| SCHEMBL19694832 | 0.89 | KYNU (0.56) | CTSKKYNUSYKCTSBKLK5 | |
| SCHEMBL4256075 | 0.89 | KYNU (0.56) | CTSKKYNUSYKCTSBKLK5 | |
| SCHEMBL626800 | 0.89 | CASP3 (0.49) | CASP3CTSDCTSKSYKCTSB | |
| SCHEMBL4422741 | 0.89 | CASP3 (0.49) | CASP3CTSDCTSKSYKCTSB | |
| SCHEMBL10074125 | 0.89 | CASP3 (0.49) | CASP3CTSDCTSKSYKCTSB | |
| SCHEMBL14190228 | 0.85 | CTSL (0.61) | CTSKKYNUSYKCTSBKLK5 | |
| SCHEMBL5493054 | 0.84 | CASP3 (0.58) | CASP3CTSDSYKCTSBCA2 | |
| SCHEMBL7303642 | 0.84 | CTSK (0.56) | CASP3CTSKSYKCTSBREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932598-A1 | ASPARTATE ESTER INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998016502-A1 | ASPARTATE ESTER INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |