Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066089 | 0.86 | SRR (0.49) | CYP1A2PTGS1TAAR1TSHR | |
| SCHEMBL1287678 | 0.83 | EPHX1 (0.55) | EPHX1CYP1A2TRPA1ALPIPKM | |
| SCHEMBL523308 | 0.82 | EPHX1 (0.48) | EPHX1CYP1A2TRPA1ALPIPKM | |
| SCHEMBL8780026 | 0.80 | TRPA1 (0.54) | EPHX1CYP1A2TRPA1ALPIPKM | |
| SCHEMBL351699 | 0.78 | SLC6A2 (0.56) | EPHX1CYP1A2TRPA1ALPIPKM | |
| SCHEMBL3588912 | 0.78 | EPHX1 (0.55) | EPHX1CYP1A2TRPA1ALPIPKM | |
| Benzene SCHEMBL28818616 | 0.78 | SLC6A2 (0.56) | EPHX1CYP1A2TRPA1ALPIPKM | |
| SCHEMBL108646 | 0.78 | TRPA1 (0.58) | EPHX1CYP1A2TRPA1ALPIPKM | |
| SCHEMBL1833635 | 0.78 | TRPA1 (0.55) | EPHX1CYP1A2TRPA1ALPIPKM | |
| SCHEMBL4272251 | 0.77 | TAAR1 (0.52) | CYP1A2SLC7A5SLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240052081-A1 | PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS | ARKEMA FRANCE (FR) | 2024-02-15 | — | — | US | claimed |
| EP-4028480-A1 | PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS | ARKEMA FRANCE (FR) | 2022-07-20 | — | — | EP | claimed |
| CN-114651049-A | Photocurable compositions containing high refractive index monomers for 3D printing applications | 阿科玛法国公司 | 2022-06-21 | — | — | CN | claimed |
| WO-2021048628-A1 | PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS | ARKEMA FRANCE (FR) | 2021-03-18 | — | — | WO | claimed |
| CN-104961247-A | Anti-scaling treatment agent for water in boiler | GAO XU | 2015-10-07 | — | — | CN | claimed |
| EP-2091945-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2014-01-15 | — | — | EP | claimed |
| EP-2501685-A1 | [1,5]-DIAZOCIN DERIVATIVES | Mellitech (FR) | 2012-09-26 | — | — | EP | claimed |
| US-20120225892-A1 | [1,5]-Diazocin Derivatives | MELLITECH (FR) | 2012-09-06 | — | — | US | claimed |
| CN-102502976-A | High-efficiency scale inhibition and dispersion bactericide and preparation method thereof | SHANGHAI JIUAN WATER QUALITY STABILIZER FACTORY | 2012-06-20 | — | — | CN | claimed |
| CN-102372369-A | Corrosion and scale inhibitor | XUEMEI GE | 2012-03-14 | — | — | CN | claimed |
| US-5420129-A | Treatment of hypertension, ischemia, vasospasms, angina | HOFFMANN-LA ROCHE INC. (US) | 1995-05-30 | — | — | US | claimed |
| EP-0633259-A1 | Sulfonylaminopyrimidines, their preparation and their use as medicine | F. HOFFMANN-LA ROCHE AG (CH) | 1995-01-11 | — | — | EP | claimed |
| EP-0626174-A2 | Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-11-30 | — | — | EP | claimed |
| CN-1095375-A | Novel sulfonamides | HOFFMANN LA ROCHE (CH) | 1994-11-23 | — | — | CN | claimed |
| EP-0601386-A1 | Sulphonamides | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-15 | — | — | EP | claimed |
| US-5292740-A | Sulfonamides | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | claimed |
| EP-0526708-A1 | Sulfonamide, preparation and use thereof as medicine and intermediate | F. HOFFMANN-LA ROCHE AG (CH) | 1993-02-10 | — | — | EP | claimed |
| US-4349549-A | Anti-hypertensive 1-substituted spiro(piperidine-oxobenzoxazine)s | SYNTEX (U.S.A.) INC. (US) | 1982-09-14 | — | — | US | claimed |
| US-4211572-A | HYDRAULIC CEMENTS, WATER RETENTIVITY PROMOTER | TILE COUNCIL OF AMERICA, INC. (US) | 1980-07-08 | — | — | US | claimed |
| US-4127495-A | BENZYLHYDROXYETHYL CELLULOSE OR PHENYLHYDROXYETHYL HYDROXYETHYL CELLULOSE AS ANTI-REDEPOSITION ADDITIVES | HERCULES INCORPORATED (US) | 1978-11-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225892-A1 | [1,5]-Diazocin Derivatives | IAPP, INSR, GLP1R | EPHX1 3695/4885CYP1A2 2743/4885TRPA1 2643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.