Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.30 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.30 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.30 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.30 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.30 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.30 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.30 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.30 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.30 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.30 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.30 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10078387 | 0.89 | HDAC1 (0.33) | RENHDAC1HDAC6DPP4DPP8 | |
| SCHEMBL10074283 | 0.78 | REN (0.37) | RENHDAC1HDAC6DPP4DPP8 | |
| SCHEMBL10074317 | 0.76 | CTSS (0.35) | RENDPP4DPP7PSMB11PSMA7 | |
| SCHEMBL10078386 | 0.76 | CTSS (0.35) | RENDPP4DPP7PSMB11PSMA7 | |
| SCHEMBL10074284 | 0.76 | CTSS (0.35) | RENDPP4DPP7PSMB11PSMA7 | |
| SCHEMBL10074292 | 0.75 | DPP4 (0.43) | RENDPP4DPP8DPP9DPP7 | |
| SCHEMBL10074134 | 0.75 | DPP4 (0.43) | RENDPP4DPP8DPP9DPP7 | |
| SCHEMBL10074293 | 0.75 | DPP4 (0.43) | RENDPP4DPP8DPP9DPP7 | |
| SCHEMBL10077381 | 0.75 | DPP4 (0.43) | RENDPP4DPP8DPP9DPP7 | |
| SCHEMBL13195333 | 0.71 | BACE1 (0.37) | RENDPP4DPP9DPP7PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418196-A1 | Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors | IMTM GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |