SCHEMBL1007439

SCHEMBL1007439

NC(=O)CCN1CCCC1

nearest known ligand 0.95

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.95
ALDH1A1 P00352 6/20 0.60
MAPT P10636 3/20 0.60
POLB P06746 2/20 0.60
CYP1A2 P05177 1/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KMT2A Q03164 5/20 0.46
LMNA P02545 2/20 0.45
GFER P55789 1/20 0.44
TSHR P16473 1/20 0.42
MEN1 O00255 1/20 0.42
HRH3 Q9Y5N1 1/20 0.40
HSP90AA1 P07900 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1010008 0.98 L3MBTL1 (1.00) L3MBTL1ALDH1A1MAPTPOLBCYP1A2
Hydrochloric Acid SCHEMBL2673561 0.98 L3MBTL1 (0.91) L3MBTL1ALDH1A1MAPTPOLBCYP1A2
Bromide SCHEMBL5330234 0.98 L3MBTL1 (0.91) L3MBTL1ALDH1A1MAPTPOLBCYP1A2
SCHEMBL25383397 0.95 L3MBTL1 (0.95) L3MBTL1ALDH1A1MAPTPOLBCYP1A2
Hydrochloric Acid SCHEMBL2674470 0.95 L3MBTL1 (0.95) L3MBTL1ALDH1A1MAPTPOLBCYP1A2
SCHEMBL8860545 0.90 L3MBTL1 (0.77) L3MBTL1ALDH1A1MAPTPOLBCYP1A2
SCHEMBL11598668 0.90 L3MBTL1 (0.77) L3MBTL1ALDH1A1MAPTPOLBCYP1A2
SCHEMBL3926676 0.88 L3MBTL1 (0.75) L3MBTL1ALDH1A1MAPTPOLBCYP1A2
Hydrochloric Acid SCHEMBL4710262 0.86 L3MBTL1 (0.72) L3MBTL1ALDH1A1MAPTPOLBCYP1A2
SCHEMBL2877981 0.86 L3MBTL1 (0.72) L3MBTL1ALDH1A1MAPTPOLBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4301736-B1 MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS LEAD DISCOVERY CENTER GMBH (DE) 2025-10-08 EP claimed
US-10562842-B2 Use of polyaminoisoprenyl derivatives in antibiotic or antiseptic treatment UNIVERSITE D'AIX-MARSEILLE (FR) 2020-02-18 US claimed
CN-109923114-A Pyrazolopyridine derivatives as HPK1 modulators and their use for the treatment of cancer 因赛特公司 2019-06-21 CN claimed
EP-2678307-B1 USE OF POLYAMINOISOPRENYL DERIVATIVES IN ANTIBIOTIC OR ANTISEPTIC TREATMENT UNIV AIX MARSEILLE (FR) 2018-04-04 EP claimed
US-20170015617-A1 USE OF POLYAMINOISOPRENYL DERIVATIVES IN ANTIBIOTIC OR ANTISEPTIC TREATMENT UNIVERSITE D'AIX-MARSEILLE (FR) 2017-01-19 US claimed
US-9328093-B2 Selective inhibitors of ubiquitin specific protease 7, the pharmaceutical compositions thereof and their therapeutic applications HYBRIGENICS SA (FR) 2016-05-03 US claimed
US-20150072973-A1 NOVEL SELECTIVE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7, THE PHARMACEUTICAL COMPOSITIONS THEREOF AND THEIR THERAPEUTIC APPLICATIONS HYBRIGENICS SA (FR) 2015-03-12 US claimed
EP-1904439-B1 SPHINGOSINE KINASE INHIBITORS APOGEE BIOTHECHNOLOGY CORP (US) 2014-11-26 EP claimed
EP-2523938-B1 Amidoacridine derivatives useful as selective inhibitors of ubiquitin specific protease 7 HYBRIGENICS SA (FR) 2014-09-03 EP claimed
US-20140128335-A1 USE OF POLYAMINOISOPRENYL DERIVATIVES IN ANTIBIOTIC OR ANTISEPTIC TREATMENT UNIVERSITE D'AIX-MARSEILLE (FR) 2014-05-08 US claimed
US-20030125370-A1 5-ARALKYSUFONYL-3-(PYRROL-2-YLMETHYLIDENE)-2-INDOLINONE DERIVATIVES AS KINASE INHIBITORS SUGEN, INC. 2003-07-03 US claimed
US-20030069297-A1 4-aryl substituted indolinones SUGEN, INC. 2003-04-10 US claimed
WO-2002094833-A1 NOVEL PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS ELI LILLY AND COMPANY (US) 2002-11-28 WO claimed
WO-2002055517-A2 4-(HETERO)ARYL SUBSTITUTED INDOLINONES CUI JINGRONG (US) 2002-07-18 WO claimed
EP-0691961-B1 SUBSTITUTED CAPROLACTAMS AND DERIVATIVES THEREOF USEFUL FOR TREATMENT OF HIV DISEASE DU PONT PHARM CO (US) 2002-02-13 EP claimed
WO-1998025884-A1 FURTHER ANTHRAQUINONES WITH BIOLOGICAL ACTIVITY CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1998-06-18 WO claimed
EP-0830349-A1 METHOD FOR PREPARING N, N'-DISUBSTITUED CYCLIC UREAS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1998-03-25 EP claimed
EP-0794827-A1 NEW BUFFER SYSTEM FOR ELECTROPHORESIS AND USE THEREOF Pharmacia Biotech AB (SE) 1997-09-17 EP claimed
WO-1996039393-A1 METHOD FOR PREPARING N, N'-DISUBSTITUED CYCLIC UREAS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-12-12 WO claimed
WO-1996016724-A1 NEW BUFFER SYSTEM FOR ELECTROPHORESIS AND USE THEREOF PHARMACIA BIOTECH AB (SE) 1996-06-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030069297-A1 4-aryl substituted indolinones CDK5, CAMK4, TNK2 L3MBTL1 3428/4885ALDH1A1 1671/4885MAPT 2035/4885
US-20140128335-A1 USE OF POLYAMINOISOPRENYL DERIVATIVES IN ANTIBIOTIC OR ANTISEPTIC TREATMENT ABCC1, ABCB11, ABCB1 L3MBTL1 4203/4885ALDH1A1 3021/4885MAPT 4030/4885
US-20030125370-A1 5-ARALKYSUFONYL-3-(PYRROL-2-YLMETHYLIDENE)-2-INDOLINONE DERIVATIVES AS KINASE INHIBITORS DMPK, ADK, MAP3K20 L3MBTL1 4313/4885ALDH1A1 2773/4885MAPT 3167/4885
US-20170015617-A1 USE OF POLYAMINOISOPRENYL DERIVATIVES IN ANTIBIOTIC OR ANTISEPTIC TREATMENT ABCC1, ABCB11, ABCB1 L3MBTL1 4203/4885ALDH1A1 3021/4885MAPT 4030/4885
US-20150072973-A1 NOVEL SELECTIVE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7, THE PHARMACEUTICAL COMPOSITIONS THEREOF AND THEIR THERAPEUTIC APPLICATIONS USP7, SENP7, PSMA7 L3MBTL1 2442/4885ALDH1A1 3216/4885MAPT 704/4885
US-10562842-B2 Use of polyaminoisoprenyl derivatives in antibiotic or antiseptic treatment ABCC1, ABCB11, ABCB1 L3MBTL1 4203/4885ALDH1A1 3021/4885MAPT 4030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.