Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP12 | P39900 | 2/20 | 0.31 |
| ▸ | MMP14 | P50281 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8228528 | 0.79 | CYP2C19 (0.44) | CYP2C19 | |
| SCHEMBL22450066 | 0.76 | — | — | |
| SCHEMBL9518366 | 0.76 | — | — | |
| SCHEMBL13594982 | 0.73 | MME (0.33) | CYP2C19 | |
| Phosphoric Acid SCHEMBL29182602 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL10049352 | 0.72 | PIK3CD (0.34) | MMP2MMP9MMP12MMP14 | |
| SCHEMBL1524639 | 0.71 | — | — | |
| SCHEMBL30642653 | 0.68 | MT-CO2 (0.52) | — | |
| SCHEMBL8222968 | 0.68 | DPP4 (0.33) | MMP2MMP9MMP12MMP14 | |
| SCHEMBL15264476 | 0.68 | KMT2A (0.33) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093386-B2 | Thioaryl substituted inhibitors of zinc proteases and their use | BRACCO IMAGING S.P.A (IT) | 2012-01-10 | — | — | US | disclosed |
| US-20090239829-A1 | THIOARYL SUBSTITUTED INHIBITORS OF ZINC PROTEASES AND THEIR USE | BRACCO IMAGING SPA (IT) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239829-A1 | THIOARYL SUBSTITUTED INHIBITORS OF ZINC PROTEASES AND THEIR USE | SERPINB1, ZFX, MMP2 | CYP2C19 353/4885MMP2 3/4885MMP9 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.