Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NT5E | P21589 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.46 |
| ▸ | ACP1 | P24666 | 2/20 | 0.46 |
| ▸ | PTPRF | P10586 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 2/20 | 0.40 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14344859 | 0.88 | GPBAR1 (0.66) | GPBAR1LMNASMN1; SMN2NT5EPTPN1 | |
| SCHEMBL19338166 | 0.88 | GPBAR1 (0.66) | GPBAR1LMNASMN1; SMN2NT5EPTPN1 | |
| SCHEMBL25466390 | 0.81 | GPBAR1 (0.49) | GPBAR1LMNASMN1; SMN2NT5EPTPN1 | |
| SCHEMBL12386420 | 0.81 | GPBAR1 (0.82) | GPBAR1LMNASMN1; SMN2NT5EPTPN1 | |
| SCHEMBL21149779 | 0.80 | LMNA (0.53) | GPBAR1LMNASMN1; SMN2NT5EPTPN1 | |
| SCHEMBL13759952 | 0.80 | LMNA (0.52) | GPBAR1LMNASMN1; SMN2NT5EPTPN1 | |
| SCHEMBL13759951 | 0.80 | LMNA (0.52) | GPBAR1LMNASMN1; SMN2NT5EPTPN1 | |
| SCHEMBL19415286 | 0.80 | LMNA (0.49) | GPBAR1LMNASMN1; SMN2NT5EPTPN1 | |
| SCHEMBL15947464 | 0.80 | LMNA (0.49) | GPBAR1LMNASMN1; SMN2NT5EPTPN1 | |
| SCHEMBL19338168 | 0.78 | LMNA (0.50) | GPBAR1LMNASMN1; SMN2NT5EPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088757-B2 | Betulinol derivatives as anti-cancer agents | BIORINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-20090176753-A1 | Betulinol derivatives as anti-cancer agents | SAXENA RESEARCH, LLC | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176753-A1 | Betulinol derivatives as anti-cancer agents | BET1, BRDT, BRCA1 | GPBAR1 650/4885LMNA 3645/4885SMN1; SMN2 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.