Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.31 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.31 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.31 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.31 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.31 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.31 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074284 | 0.91 | CTSS (0.35) | CTSSCTSBMMP12SCN9ACYP3A4 | |
| SCHEMBL10078386 | 0.91 | CTSS (0.35) | CTSSCTSBMMP12SCN9ACYP3A4 | |
| SCHEMBL10074317 | 0.91 | CTSS (0.35) | CTSSCTSBMMP12SCN9ACYP3A4 | |
| SCHEMBL10074719 | 0.91 | CTSS (0.41) | CTSSCTSBSCN9ACTSDREN | |
| SCHEMBL10078262 | 0.87 | MMP12 (0.36) | CTSSCTSBMMP12SCN9ACYP3A4 | |
| SCHEMBL10074733 | 0.85 | CTSD (0.33) | CTSDRENDPP4 | |
| SCHEMBL10078388 | 0.85 | CTSD (0.33) | CTSDRENDPP4 | |
| SCHEMBL10074286 | 0.85 | CTSD (0.33) | CTSDRENDPP4 | |
| SCHEMBL10074282 | 0.84 | CTSS (0.40) | CTSSCTSBSCN9ACTSDREN | |
| SCHEMBL10074290 | 0.84 | CTSS (0.40) | CTSSCTSBSCN9ACTSDREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418196-A1 | Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors | IMTM GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |