SCHEMBL10075784

SCHEMBL10075784

CC(=O)O/N=C(\C)C(=O)c1ccc(Sc2ccc(OCCO)cc2)cc1O

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 1/20 0.37
MAOB P27338 14/20 0.35
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
POLB P06746 1/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20709770 0.90 PPARD (0.37) PPARDMAOBSMN1; SMN2LMNACYP3A4
SCHEMBL10075731 0.89 GAA (0.35) GAASMN1; SMN2LMNACYP3A4
SCHEMBL20709768 0.89 MAOB (0.35) PPARDMAOBGAA
SCHEMBL10075763 0.87 THRA (0.34) GAASMN1; SMN2LMNACYP3A4
SCHEMBL10075766 0.87 KDM4E (0.36) GAASMN1; SMN2LMNACYP3A4
SCHEMBL10075781 0.86 SMN1; SMN2 (0.32) GAASMN1; SMN2LMNACYP3A4
SCHEMBL19751028 0.86 PPARD (0.35) PPARDMAOBGAASMN1; SMN2LMNA
SCHEMBL10075786 0.85 SLC6A2 (0.31) GAASMN1; SMN2POLB
SCHEMBL10075773 0.85 MAPT (0.32) GAASMN1; SMN2LMNA
SCHEMBL22639048 0.84 GAA (0.43) GAASMN1; SMN2LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2586827-B1 CURABLE RESIN COMPOSITION ADEKA CORP (JP) 2017-12-27 EP disclosed
US-8735511-B2 Curing resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
US-8735511-B2 Curing resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
US-20120115972-A1 CURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-05-10 US disclosed
US-20120115972-A1 CURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-05-10 US disclosed
US-8148045-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-04-03 US disclosed
US-8148045-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-04-03 US disclosed
EP-2327689-B1 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORP (JP) 2012-02-29 EP disclosed
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-02 US disclosed
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-02 US disclosed
EP-2327689-A1 Oxime ester compound and photopolymerization initiator containing the same Adeka Corporation (JP) 2011-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME OXER1, OR10J3, CDK11B PPARD 2616/4885MAOB 1080/4885GAA 4794/4885
US-20120115972-A1 CURING RESIN COMPOSITION LTA, LOXL1, PLOD2 PPARD 766/4885MAOB 666/4885GAA 3567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.