Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL6827958 | 0.98 | TSHR (0.43) | TSHRALDH1A1TDP1L3MBTL1GAA | |
| Butane SCHEMBL5526854 | 0.94 | TSHR (0.41) | TSHRALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL21925526 | 0.92 | TSHR (0.39) | TSHRALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL243431 | 0.87 | TSHR (0.56) | TSHRALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL10668310 | 0.85 | MGAM (0.34) | TSHRALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL11880082 | 0.84 | MAPT (0.50) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL28236036 | 0.83 | TSHR (0.52) | TSHRALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL27964667 | 0.83 | TSHR (0.52) | TSHRALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL6516125 | 0.82 | TSHR (0.42) | TSHRALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL6516117 | 0.82 | TSHR (0.42) | TSHRALDH1A1TDP1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4368686-B1 | LUBRICITY IMPROVER COMPOSITION FOR FUEL OIL AND USE THEREOF | CHINA PETROLEUM & CHEM CORP (CN) | 2026-05-27 | — | — | EP | disclosed |
| US-12637680-B2 | Recombinant host cells for the production of malonate | LYGOS, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| US-12365847-B2 | Lubricity improver composition for fuel oil and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2025-07-22 | — | — | US | disclosed |
| CN-119709450-A | Recombinant host cells for malonate production | 利戈斯股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-114616330-B | Recombinant host cells for malonate production | 利戈斯股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-20240368490-A1 | LUBRICITY IMPROVER COMPOSITION FOR FUEL OIL AND USE THEREOF | Sinopec Research Institute of Petroleum Processing Co., Ltd. (CN) | 2024-11-07 | — | — | US | disclosed |
| EP-4393937-A1 | STEROID COMPOUND AND CONJUGATE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| US-20240191216-A1 | RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE | LYGOS, INC. (US) | 2024-06-13 | — | — | US | disclosed |
| EP-4374877-A2 | PHARMACEUTICAL CONTAINING SODIUM-DEPENDENT PHOSPHATE TRANSPORTER INHIBITOR AND PHOSPHORUS ADSORBENT FOR USE IN THE PREVENTION, TREATMENT OR SUPPRESSION OF CHRONIC KIDNEY DISEASE, ARTERIOSCLEROSIS ASSOCIATED WITH VASCULAR CALCIFICATION, OR ECTOPIC CALCIFICATION. | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-29 | — | — | EP | disclosed |
| CN-118086086-A | Recombinant host cells for malonate production | 利戈斯股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-102176820-A | Liquid crop protection formulations containing pyraclostrobin | BASF SE | 2011-09-07 | — | — | CN | disclosed |
| US-20110118172-A1 | METASTIN DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-2277900-A1 | METASTIN DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2011-01-26 | — | — | EP | disclosed |
| CN-1100067-C | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 2003-01-29 | — | — | CN | disclosed |
| EP-0847974-B1 | Process for the preparation of cyclopropylacetylene and its derivatives | KURARAY CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5955627-A | Process for the preparation of cyclopropylacetylene derivatives | KURARAY CO., LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| US-5861427-A | ALLEVIATION OF OSTEOARTHRITIS, RHEUMATOID ARTHRITIS, SEPTIC ARTHRITIS, PERIODONTAL DISEASE, CORNEAL ULCERATION, PROTEINURIA, ANEURYSMAL AORTIC DISEASE, DYSTROPHOBIC EPIDERMOLYSIS BULLOSA, CONDITIONS LEADING TO INFLAMMATORY | BAYER HEALTHCARE LLC | 1999-01-19 | — | — | US | disclosed |
| EP-0847974-A1 | Process for the preparation of cyclopropylacetylene and its derivatives | KURARAY CO., LTD. (JP) | 1998-06-17 | — | — | EP | disclosed |
| US-4602118-A | AROMATIC KETONES CONTAINING ELECTROPHILIC GROUPS ARE PROMOTERS | EXXON RESEARCH AND ENGINEERING CO. (US) | 1986-07-22 | — | — | US | disclosed |
| EP-0082088-A1 | Derivatives of amino acids and their therapeutic use | Roques, Bernard (FR) | 1983-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118172-A1 | METASTIN DERIVATIVE AND USE THEREOF | GNRHR, SHBG, INHA | TSHR 1334/4885ALDH1A1 3515/4885TDP1 4668/4885 |
| US-12637680-B2 | Recombinant host cells for the production of malonate | DCXR, ETV1, LYPLA2 | TSHR 1351/4885ALDH1A1 1554/4885TDP1 3582/4885 |
| US-20240191216-A1 | RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE | ME1, MAL2, ME3 | TSHR 2970/4885ALDH1A1 2274/4885TDP1 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.