⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007642 | 1.00 | — | — | |
| SCHEMBL6925684 | 0.80 | — | — | |
| SCHEMBL14556395 | 0.80 | — | — | |
| SCHEMBL24167503 | 0.77 | NOS1 (0.55) | — | |
| SCHEMBL12262029 | 0.76 | CES2 (0.52) | — | |
| SCHEMBL13739852 | 0.76 | CES2 (0.52) | — | |
| SCHEMBL15818576 | 0.75 | CES2 (0.56) | — | |
| SCHEMBL15818574 | 0.75 | CES2 (0.56) | — | |
| SCHEMBL9769960 | 0.75 | CES2 (0.52) | — | |
| SCHEMBL11760036 | 0.75 | NOS1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4363415-B1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | TECNIMEDE SOCIEDADE TECNICO MEDICINAL SA (PT) | 2025-12-10 | — | — | EP | disclosed |
| US-20240279217-A1 | Heterocyclic compounds for the treatment of tuberculosis | TECNIMEDE - Sociedade Técnico-medicinal, SA (PT) | 2024-08-22 | — | — | US | disclosed |
| EP-4363415-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | Tecnimede, Sociedade Técnico-Medicinal, SA (PT) | 2024-05-08 | — | — | EP | disclosed |
| WO-2023275744-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | TECNIMEDE - Sociedade Técnico-medicinal, SA (PT) | 2023-01-05 | — | — | WO | disclosed |
| WO-2023275744-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | TECNIMEDE - Sociedade Técnico-medicinal, SA (PT) | 2023-01-05 | — | — | WO | disclosed |
| EP-2956453-B1 | 3,5-DISUBSTITUTED-4,5-DIHYDRO-1,2,4-OXADIAZOLES FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2019-10-02 | — | — | EP | disclosed |
| US-9232800-B2 | 3,5-disubstituted-4,5-dihydro-1,2,4-oxadiazoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2016-01-12 | — | — | US | disclosed |
| EP-2956453-A1 | 3,5-DISUBSTITUTED-4,5-DIHYDRO-1,2,4-OXADIAZOLES FOR CONTROLLING NEMATODE PESTS | Monsanto Technology LLC (US) | 2015-12-23 | — | — | EP | disclosed |
| WO-2014127195-A1 | 3,5-DISUBSTITUTED-4,5-DIHYDRO-1,2,4-OXADIAZOLES FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2014-08-21 | — | — | WO | disclosed |
| US-20140235439-A1 | 3,5-DISUBSTITUTED-4,5-DIHYDRO-1,2,4-OXADIAZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2014-08-21 | — | — | US | disclosed |
| US-7459452-B2 | Dihydroxypyrimidine carboxamide inhibitors of HIV integrase | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2008-12-02 | — | — | US | disclosed |
| US-20070208021-A1 | Phenoxyacetic Acid Derivatives and Drug Comprising The Same | DAIICHI PHARMACEUTICAL CO., LTD. | 2007-09-06 | — | — | US | disclosed |
| US-20070208021-A1 | Phenoxyacetic Acid Derivatives and Drug Comprising The Same | DAIICHI PHARMACEUTICAL CO., LTD. | 2007-09-06 | — | — | US | disclosed |
| US-20070203138-A1 | Novel Compounds and Compositions as Cathepsin S Inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-08-30 | — | — | US | disclosed |
| US-20070203138-A1 | Novel Compounds and Compositions as Cathepsin S Inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-08-30 | — | — | US | disclosed |
| US-7232819-B2 | Dihydroxypyrimidine carboxamide inhibitors of HIV integrase | ISTITUTO DI RICERCHE DI BIOLOGIA P. ANGELETTI S.P.A. (IT) | 2007-06-19 | — | — | US | disclosed |
| US-7226921-B2 | Compounds and compositions as cathepsin S inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-06-05 | — | — | US | disclosed |
| US-20070083045-A1 | Dihydroxypyrimidine carboxamide inhibitors of HIV integrase | DI FRANCESCO MARIA E | 2007-04-12 | — | — | US | disclosed |
| EP-1441734-B1 | DIHYDROXYPYRIMIDINE CARBOXAMIDE INHIBITORS OF HIV INTEGRASE | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-02-28 | — | — | EP | disclosed |
| US-20050075356-A1 | Dihydroxypyrimidine carboxamide inhibitors of hiv integrase | ISTITUTO DI RICHERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2005-04-07 | — | — | US | disclosed |