⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007641 | 1.00 | — | — | |
| SCHEMBL6925684 | 0.80 | — | — | |
| SCHEMBL14556395 | 0.80 | — | — | |
| SCHEMBL24167503 | 0.77 | NOS1 (0.55) | — | |
| SCHEMBL12262029 | 0.76 | CES2 (0.52) | — | |
| SCHEMBL13739852 | 0.76 | CES2 (0.52) | — | |
| SCHEMBL15818576 | 0.75 | CES2 (0.56) | — | |
| SCHEMBL15818574 | 0.75 | CES2 (0.56) | — | |
| SCHEMBL9769960 | 0.75 | CES2 (0.52) | — | |
| SCHEMBL11760036 | 0.75 | NOS1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 736 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581525-A2 | COMPOUNDS HAVING AN ACTIVITY AT METABOTROPIC GLUTAMATE RECEPTORS | AstraZeneca AB (SE) | 2005-10-05 | — | — | EP | claimed |
| US-20040106607-A1 | New compounds | ASTRAZENECA AB AND NPS PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | claimed |
| WO-2004014902-A2 | COMPOUNDS HAVING AN ACTIVITY AT METABOTROPIC GLUTAMATE RECEPTORS | ASTRAZENECA AB (SE) | 2004-02-19 | — | — | WO | claimed |
| US-6423486-B1 | — | — | None | — | — | US | disclosed |
| CN-114957235-B | Benzothiazinone derivatives, preparation method and application thereof | 四川大学华西医院 | 2023-10-24 | — | — | CN | disclosed |
| CN-116504432-A | Decontamination composite solution and preparation method and application of gel film thereof | 中国原子能科学研究院 | 2023-07-28 | — | — | CN | disclosed |
| CN-115093377-B | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | disclosed |
| US-20230091947-A1 | ALTERNATING CURRENT ELECTROLYSIS FOR USE IN ORGANIC SYNTHESIS | WAYNE STATE UNIVERSITY (US) | 2023-03-23 | — | — | US | disclosed |
| CN-115093377-A | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-114957235-A | Benzothiazinone derivative and preparation method and application thereof | 四川大学华西医院 | 2022-08-30 | — | — | CN | disclosed |
| US-20210207274-A1 | ALTERNATING CURRENT ELECTROLYSIS FOR USE IN ORGANIC SYNTHESIS | WAYNE STATE UNIVERSITY (US) | 2021-07-08 | — | — | US | disclosed |
| EP-0259621-A2 | Piperidine compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1988-03-16 | — | — | EP | disclosed |
| EP-0225013-A1 | Heterocyclic compounds and their preparation and use | A/S FERROSAN (DK) | 1987-06-10 | — | — | EP | disclosed |
| US-4324579-A | Herbicidal and phytohormonal amidoximes | PHILARGO (FR) | 1982-04-13 | — | — | US | disclosed |
| US-4216006-A | Herbicidal and phytohormonal amidoximes | PHILAGRO (FR) | 1980-08-05 | — | — | US | disclosed |
| US-4188203-A | Herbicidal and phytohormonal amidoximes | PHILAGRO (FR) | 1980-02-12 | — | — | US | disclosed |
| US-4154598-A | Herbicidal 1,2,4-oxadiazin-5-one compositions | PHILAGRO (FR) | 1979-05-15 | — | — | US | disclosed |
| US-4116974-A | HERBICIDAL AND PHYTOHORMONAL AMIDOXIMES | PHILAGRO (FR) | 1978-09-26 | — | — | US | disclosed |
| US-4065563-A | 3-Hetero-5-isothiocyanophenyl oxadiazoles as antifungal and antibacterial agents | E. R. SQUIBB & SONS, INC. (US) | 1977-12-27 | — | — | US | disclosed |
| US-4022901-A | FUNGICIDAL AND BACTERICIDAL ACTIVITY | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | disclosed |