Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1924038 | 0.81 | CYP2A6 (0.42) | PDGFRBPDGFRAHPGDSRAB9AMAPK10 | |
| SCHEMBL486937 | 0.77 | PDGFRB (0.65) | PDGFRBPDGFRAPARP1RAB9ACYP2A6 | |
| SCHEMBL31441068 | 0.77 | PDGFRB (0.65) | PDGFRBPDGFRAPARP1RAB9ACYP2A6 | |
| SCHEMBL28251009 | 0.74 | PDGFRB (0.36) | PDGFRBPDGFRAHPGDSMAPK10CYP2A6 | |
| SCHEMBL1519758 | 0.73 | CYP3A4 (0.49) | IMPDH2 | |
| SCHEMBL13397489 | 0.73 | PRKCZ (0.46) | IMPDH2CSNK1DCSNK1ECLK1DYRK1A | |
| SCHEMBL3367827 | 0.73 | EGFR (0.49) | PDGFRBPDGFRAPARP1RAB9ADYRK1A | |
| SCHEMBL7938841 | 0.73 | HTT (0.46) | PDGFRBPDGFRAPARP1RAB9ACYP2A6 | |
| SCHEMBL13544033 | 0.73 | ALDH1A1 (0.46) | PDGFRBPDGFRAPARP1CYP2A6KDM4E | |
| SCHEMBL25216279 | 0.71 | PDGFRB (0.47) | PDGFRBPDGFRAHPGDSRAB9AMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267953-A | Tetrahydroimidazo [4,5-C ] pyridine derivatives as inducers of PD-L1 internalization | 因赛特公司 | 2019-09-20 | — | — | CN | disclosed |
| EP-2081922-B1 | 5,6-Ring annulated indole derivatives and use thereof | SCHERING CORP (US) | 2012-02-01 | — | — | EP | disclosed |