Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.42 |
| ▸ | MELK | Q14680 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1519758 | 0.92 | CYP3A4 (0.49) | IMPDH2CYP3A4CYP19A1 | |
| SCHEMBL2006719 | 0.80 | PRKCZ (0.46) | PRKCZCYP3A4MELKCYP19A1TBXAS1 | |
| SCHEMBL2098638 | 0.78 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL29434157 | 0.78 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL30579893 | 0.77 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL22113182 | 0.77 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL2097335 | 0.75 | ALDH1A1 (0.59) | ALDH1A1 | |
| SCHEMBL29434184 | 0.75 | ALDH1A1 (0.59) | ALDH1A1 | |
| Pyridine SCHEMBL1875987 | 0.73 | RELA (0.50) | CYP3A4CYP19A1ALDH1A1 | |
| SCHEMBL10077016 | 0.73 | PDGFRB (0.40) | IMPDH2CSNK1DCSNK1ECLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-3633380-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1 | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018039621-A1 | INHIBITION OF OLIG2 ACTIVITY | Curtana Pharmaceuticals, Inc. (US) | 2018-03-01 | — | — | WO | disclosed |
| EP-2177526-A1 | 10A-AZALIDE COMPOUND CROSSLINKED AT POSITION-10A AND POSITION-12 | Taisho Pharmaceutical Co. Ltd. (JP) | 2010-04-21 | — | — | EP | disclosed |