Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NGFR | P08138 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CLTC | Q00610 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11505795 | 0.80 | PTPN1 (0.47) | ERN1TDP1TSHRMEN1KMT2A | |
| SCHEMBL27528864 | 0.67 | MAPK1 (0.56) | TDP1TSHRMEN1KMT2AMAPT | |
| SCHEMBL17348525 | 0.66 | ERN1 (0.57) | ERN1TDP1MEN1KMT2APOLB | |
| SCHEMBL9669264 | 0.66 | TDP1 (0.62) | ERN1TDP1TSHRMEN1KMT2A | |
| SCHEMBL11121651 | 0.65 | HTT (0.44) | ERN1POLBMAPTALDH1A1 | |
| SCHEMBL29903867 | 0.64 | TSHR (0.58) | TDP1TSHRFTOPABPC1MEN1 | |
| SCHEMBL10788183 | 0.64 | TSHR (0.58) | TDP1TSHRFTOPABPC1MEN1 | |
| SCHEMBL11428771 | 0.64 | CLTC (0.50) | TDP1TSHRMEN1KMT2APOLB | |
| SCHEMBL11806980 | 0.62 | NR4A1 (0.46) | TDP1TSHRMEN1KMT2APOLB | |
| SCHEMBL29607767 | 0.62 | ERN1 (0.60) | ERN1TDP1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507778-B1 | ANTI-TUMOUR POLYCYCLIC CARBOXAMIDES | UNIV TROBE (AU) | 2012-02-22 | — | — | EP | disclosed |