Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17348583 | 0.85 | VCAM1 (0.49) | ERN1MAPTKDM4ETDP1GPR35 | |
| SCHEMBL4756022 | 0.80 | ERN1 (0.63) | ERN1MAPTKDM4ETDP1GPR35 | |
| SCHEMBL16838207 | 0.79 | ERN1 (0.61) | ERN1MAPTKDM4ETDP1GPR35 | |
| SCHEMBL12492120 | 0.77 | ERN1 (0.69) | ERN1MAPTKDM4ETDP1GPR35 | |
| SCHEMBL2771759 | 0.77 | ERN1 (0.59) | ERN1MAPTKDM4ETDP1GPR35 | |
| SCHEMBL17348557 | 0.76 | GPR35 (0.54) | ERN1MAPTKDM4ETDP1GPR35 | |
| SCHEMBL918368 | 0.73 | ERN1 (0.73) | ERN1MAPTGPR35ALDH1A1TTR | |
| SCHEMBL30135697 | 0.73 | ERN1 (1.00) | ERN1MAPTKDM4ETDP1GPR35 | |
| SCHEMBL79298 | 0.73 | ERN1 (1.00) | ERN1MAPTKDM4ETDP1GPR35 | |
| SCHEMBL17348559 | 0.72 | ERN1 (0.42) | ERN1MAPTKDM4ETDP1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015191640-A2 | BICYCLIC XANTHINE OXIDASE INHIBITORS AND METHODS OF USE | BAYLOR COLLEGE OF MEDICINE (US) | 2015-12-17 | — | — | WO | disclosed |