Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CLTC | Q00610 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428771 | 0.84 | CLTC (0.50) | PTPN1CLTCTP53HSD17B10TDP1 | |
| SCHEMBL10077333 | 0.80 | ERN1 (0.39) | PTPN1CLTCERN1TDP1TSHR | |
| SCHEMBL3895684 | 0.78 | CLTC (0.46) | PTPN1CLTCTP53HSD17B10TDP1 | |
| SCHEMBL2142577 | 0.76 | ERN1 (0.50) | ERN1TP53HSD17B10TDP1TSHR | |
| SCHEMBL1688876 | 0.75 | HSD17B10 (0.60) | PTPN1ERN1HSD17B10TDP1TSHR | |
| SCHEMBL29563927 | 0.75 | HSD17B10 (0.60) | PTPN1ERN1HSD17B10TDP1TSHR | |
| SCHEMBL23409361 | 0.74 | CLTC (0.47) | PTPN1CLTCTP53TDP1TSHR | |
| SCHEMBL30247949 | 0.74 | CLTC (0.47) | PTPN1CLTCTP53TDP1TSHR | |
| SCHEMBL24837592 | 0.74 | CLTC (0.47) | PTPN1CLTCTP53TDP1TSHR | |
| SCHEMBL22163989 | 0.74 | ERN1 (0.62) | ERN1TP53TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699241-A | Polyalkyleneimino polymers with polyester groups | 巴斯夫欧洲公司 | 2018-10-23 | — | — | CN | disclosed |
| US-4151174-A | 1:1 Adducts of indole and (na)phthalaldehydic acid | POLAROID CORPORATION (US) | 1979-04-24 | — | — | US | disclosed |
| US-4036863-A | Trinapthylmethane compounds | POLAROID CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |
| US-3976662-A | 1:1 Adducts of 1-naphthol and (Na)phthalaldehydic acid | POLAROID CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |