Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 2/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FGF1 | P05230 | 2/20 | 0.37 |
| ▸ | FGF2 | P09038 | 2/20 | 0.37 |
| ▸ | VEGFA | P15692 | 2/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2629592 | 1.00 | LGALS8 (0.48) | LGALS8NT5ESLC6A2SSTR5SSTR1 | |
| SCHEMBL14075622 | 1.00 | LGALS8 (0.48) | LGALS8NT5ESLC6A2SSTR5SSTR1 | |
| SCHEMBL2629582 | 0.91 | LGALS8 (0.42) | LGALS8NT5ESLC6A2SSTR5SSTR1 | |
| SCHEMBL472852 | 0.91 | LGALS8 (0.42) | LGALS8NT5ESLC6A2SSTR5SSTR1 | |
| SCHEMBL14075626 | 0.91 | LGALS8 (0.42) | LGALS8NT5ESLC6A2SSTR5SSTR1 | |
| SCHEMBL2629589 | 0.87 | LGALS8 (0.43) | LGALS8NT5ESLC6A2SSTR5SSTR1 | |
| SCHEMBL472845 | 0.87 | LGALS8 (0.43) | LGALS8NT5ESLC6A2SSTR5SSTR1 | |
| SCHEMBL14075623 | 0.87 | LGALS8 (0.43) | LGALS8NT5ESLC6A2SSTR5SSTR1 | |
| SCHEMBL10077913 | 0.87 | LGALS8 (0.39) | LGALS8NT5ESLC6A2SSTR5SSTR1 | |
| SCHEMBL14409790 | 0.86 | NT5E (0.51) | NT5ESSTR5SSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637578-B2 | Reagents and methods for the formation of disulfide bonds and the glycosylation of proteins | ISIS INNOVATION LIMITED (GB) | 2014-01-28 | — | — | US | disclosed |
| US-20070213506-A1 | Reagents And Methods For The Formation Of Disulfide Bonds And The Glycosylation Of Proteins | ISIS INNOVATION LIMITED (GB) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213506-A1 | Reagents And Methods For The Formation Of Disulfide Bonds And The Glycosylation Of Proteins | SCLY, PTMS, TST | LGALS8 1044/4885NT5E 3172/4885SLC6A2 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.