Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.45 |
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85784 | 0.88 | TAAR1 (0.53) | TAAR1HTR2ADRD2DRD1PLAU | |
| SCHEMBL92637 | 0.83 | TAAR1 (0.58) | TAAR1MAOBHRH1HRH4HTR7 | |
| SCHEMBL10198677 | 0.81 | TAAR1 (0.45) | TAAR1HTR7HTR2A | |
| SCHEMBL880647 | 0.80 | PTGES (0.32) | TAAR1PTGES | |
| SCHEMBL15805926 | 0.77 | TAAR1 (0.42) | TAAR1HTR2ADRD2DRD1PLAU | |
| SCHEMBL10119152 | 0.73 | TAAR1 (0.38) | TAAR1 | |
| SCHEMBL15138969 | 0.71 | TAAR1 (0.53) | TAAR1MAOBHTR7HTR2ADRD2 | |
| SCHEMBL880646 | 0.70 | L3MBTL1 (0.40) | MAOB | |
| SCHEMBL10198719 | 0.70 | TAAR1 (0.38) | TAAR1PTGES | |
| SCHEMBL15805947 | 0.69 | HSD17B1 (0.43) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468711-A2 | Facially amphiphilic polyaryl and polarylalkynyl polymers and oligomers and uses thereof | The Trustees Of The University Of Pennsylvania (US) | 2012-06-27 | — | — | EP | disclosed |
| EP-2433627-A1 | Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer | The Trustees Of The University Of Pennsylvania (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2012006315-A2 | METHODS OF IMMUNE MODULATION | POLYMEDIX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
| EP-2298074-A2 | Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer | The Trustees Of The University Of Pennsylvania (US) | 2011-03-23 | — | — | EP | disclosed |
| WO-2008083256-A2 | OPHTHALMIC AND OTIC COMPOSITIONS OF FACIALLY AMPHIPHILIC POLYMERS AND OLIGOMERS AND USES THEREOF | POLYMEDIX, INC. (US) | 2008-07-10 | — | — | WO | disclosed |